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2-Methoxyethoxymethyl chloride

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Products Intro: Product Name:2-Methoxyethoxy methyl Chloride
CAS:3970-21-6
Purity:97% (Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
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Products Intro: Product Name:2-Methoxyethoxymethyl chloride
CAS:3970-21-6
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
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Products Intro: Product Name:3970-21-6
CAS:3970-21-6
Purity:0.99 Package:25KG,5KG;1KG;500G
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Products Intro: CAS:3970-21-6
Purity:98% Package:g-Kg Remarks:Colorless transparent liquid
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Products Intro: Product Name:2-Methoxyethoxymethyl chloride
CAS:3970-21-6
Purity:98% Package:1KG;1USD

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2-Methoxyethoxymethyl chloride Basic information
Product Name:2-Methoxyethoxymethyl chloride
Synonyms:ALKOXYETHOXYMETHYLCHLORIDE;BETA-METHOXYETHOXYMETHYL CHLORIDE;ETHYLENE GLYCOL CHLOROMETHYL METHYL ETHER;MEM CHLORIDE;1-CHLOROMETHOXY-2-METHOXYETHANE;1-(Chloromethoxy)-2-methoxyethane~MEM chloride;Alcoxyethoxymethylchloride;Methoxxxy ethoxy Chloromethane
CAS:3970-21-6
MF:C4H9ClO2
MW:124.57
EINECS:223-589-8
Product Categories:Protection & Derivatization Reagents (for Synthesis);Synthetic Organic Chemistry
Mol File:3970-21-6.mol
2-Methoxyethoxymethyl chloride Structure
2-Methoxyethoxymethyl chloride Chemical Properties
Melting point 200-202 °C
Boiling point 50-52 °C/13 mmHg (lit.)
density 1.091 g/mL at 25 °C (lit.)
refractive index n20/D 1.427(lit.)
Fp >230 °F
storage temp. 2-8°C
form Liquid
Specific Gravity1.091
color Clear colorless to yellow
Water Solubility It hydrolyzes with water.
Sensitive Moisture Sensitive
BRN 1900576
InChIKeyBIAAQBNMRITRDV-UHFFFAOYSA-N
CAS DataBase Reference3970-21-6(CAS DataBase Reference)
NIST Chemistry Reference«BETA»-methoxyethoxymethyl chloride(3970-21-6)
EPA Substance Registry SystemEthane, 1-(chloromethoxy)-2-methoxy- (3970-21-6)
Safety Information
Hazard Codes T
Risk Statements 45-10-36/37/38-20/21/22-46-40-23/24/25-20/22
Safety Statements 53-26-36/37/39-45-16-23
RIDADR UN 2810 6.1/PG 2
WGK Germany 3
10-21
Hazard Note Toxic
TSCA Yes
HazardClass 3
PackingGroup III
HS Code 29091990
MSDS Information
ProviderLanguage
beta-Methoxyethoxymethyl chloride English
SigmaAldrich English
ACROS English
ALFA English
2-Methoxyethoxymethyl chloride Usage And Synthesis
Chemical PropertiesCLEAR COLOURLESS LIQUID
Uses2-Methoxyethoxymethyl Chloride is an OH-protecting reagent. 2-Methoxyethoxymethyl Chloride is used in the modification of antibiotics.
Purification MethodsPossible impurities are methoxyethanol (b 124o/atm), HCHO and HCl which can be removed below the boiling point of MEMCl. Purify MEMCl by fractional distillation in a vacuum. If too impure, prepare it from methoxyethanol (152g) and s-trioxane (66g) by bubbling a stream of dry HCl (with stirring) until a clear mixture is obtained. Dilute with pentane (900mL), dry (3hours over 100g MgSO4, at 5o), evaporate and the residue is distilled in a vacuum. It is MOISTURE SENSITIVE and TOXIC. The MEM.NEt3+Cl-salt, prepared by reaction with 1.3 equivalents of Et3N (16hours/25o) and dried in a vacuum, has m 58-61o, and is moisture sensitive. [Corey et al. Tetrahedron Lett 809 1976, Yoshimatsu et al. J Org Chem 59 1011 1994, Greene & Wuts Protective Groups in Organic Synthesis edn, J Wiley & Sons NY 1991.] Carcinogen.
2-Methoxyethoxymethyl chloride Preparation Products And Raw materials
Preparation ProductsRoxithromycin-->3,4-DIBROMO-5-HYDROXY-5H-FURAN-2-ONE-->DME-->BIS(2-METHOXYETHOXY)METHANE
Tag:2-Methoxyethoxymethyl chloride(3970-21-6) Related Product Information
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