2'-脱氧肌苷
| 中文名称 | 2'-脱氧肌苷 |
|---|---|
| 中文同义词 | 2ˊ-脱氧次黄嘌呤核苷;2ˊ-脱氧肌苷;9-(2-脱氧-Β-D-呋喃核糖基)次黄嘌呤;9-(2-脱氧-Β-D-呋喃核糖)黄嘌呤;2'-脱氧-肌苷 水合物;2'-脱氧-肌苷一水合物;9-(2-脱氧-Β-D-呋喃核糖基)次黄嘌呤2'-脱氧次黄嘌呤核苷2'-脱氧肌苷;2'-脱氧肌苷, 98+% |
| 英文名称 | 2'-Deoxyinosine |
| 英文同义词 | DEOXYINOSINE, 2'-(RG);9-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-9H-purin-6-ol;9-((2R,4S,5R)-4-Hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol;1,9-Dihydro-9-(2'-deoxy-β-D-ribofuranosyl)-6H-purin-6-one;9-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,9-dihydro-6H-purin-6-one;2'-Deoxyinosine monohydrate;2’-deoxy-inosin;Hypoxanthine, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)- |
| CAS号 | 890-38-0 |
| 分子式 | C10H12N4O4 |
| 分子量 | 252.23 |
| EINECS号 | 212-964-1 |
| 相关类别 | 生化试剂;核酸;小分子抑制剂;其他生化试剂;化学试剂;植物激素及核酸类;核苷，核苷酸，寡核苷酸;医用原料;Bases & Related Reagents;Heterocycles;Impurities;Inhibitors;Intermediates & Fine Chemicals;对照品;核苷;生化试剂-植物激素及核酸类;医用原料;有机溶剂;对照品;中药对照品;医药原料;通用生化试剂-核酸;2'-脱氧类;有机化工原料;Pharmaceutical Raw Materials;Pyridines, Pyrimidines, Purines and Pteredines;Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleotides;Pharmaceuticals;Heterocycles, Impurities, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals |
| Mol文件 | 890-38-0.mol |
| 结构式 |  |
2'-脱氧肌苷 性质
| 熔点 | 250 °C |
|---|---|
| 比旋光度 | 21 º (c=1, H2O 22 ºC) |
| 沸点 | 395.4°C (rough estimate) |
| 密度 | 1.3402 (rough estimate) |
| 折射率 | -16 ° (C=1, H2O) |
| 储存条件 | -20°C |
| 溶解度 | DMSO（少许）、水（少许） |
| 酸度系数(pKa) | 8.92±0.70(Predicted) |
| 形态 | 粉末 |
| 颜色 | 白色至类白色 |
| 水溶解性 | 8.33g/L(25.02 ºC) |
| BRN | 33517 |
| InChI | InChI=1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1 |
| InChIKey | VGONTNSXDCQUGY-RRKCRQDMSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)O)N=C2)C[C@@H]1O |
| CAS 数据库 | 890-38-0(CAS DataBase Reference) |
| NIST化学物质信息 | Inosine, 2'-deoxy-(890-38-0) |
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Human Endogenous Metabolite
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In the absence of deoxycoformycin, 2’-deoxyadenosine is primarily deaminated to 2’-deoxyinosine and then converted into hypoxanthine. In the presence of the inhibitor, the deoxynucleoside, in addition to a phosphorylation process, undergoes phosphorolytic cleavage giving rise to adenine. The conversion of 2’-deoxyadenosine to adenine might represent a protective device, emerging when the activity of adenosine deaminase is reduced or inhibited. There is much evidence to indicate that the enzyme catalyzing this processs may be distinct from methylthioadenosine phosphorylase and S-adenosyl homocysteine hydrolase, which are the enzymes reported to be responsible for the formation of adenine from 28-deoxyadenosine in mammals.
安全信息
| 危险品标志 | Xn,Xi |
|---|---|
| 危险类别码 | 20/21/22-36/37/38 |
| 安全说明 | 24/25-37/39-36-26 |
| WGK Germany | 3 |
| F | 10-23 |
| 海关编码 | 29349990 |
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/01/25 | HY-W008638 | 2'-Deoxyinosine | 50 mg | 300元 | |
| 2024/01/25 | HY-W008638 | 2'-脱氧肌苷 2'-Deoxyinosine | 890-38-0 | 10mM * 1mLin DMSO | 330元 |