Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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Tel: |
821-50328103-801 18930552037 |
Email: |
3bsc@sina.com |
Products Intro: |
Product Name:(±)-Hexanoylcarnitine chloride CAS:6920-35-0 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Company Name: |
EMMX Biotechnology LLC
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Tel: |
888-539-0666 |
Email: |
info@emmx.com |
Products Intro: |
Product Name:(±)-Hexanoylcarnitine chloride CAS:6920-35-0 Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| DL-CAPROYLCARNITINE CHLORIDE Basic information |
Product Name: | DL-CAPROYLCARNITINE CHLORIDE | Synonyms: | (+/-)-HEXANOYLCARNITINE CHLORIDE;DL-HEXANOYLCARNITINE CHLORIDE;DL-CAPROYLCARNITINE CHLORIDE;Zinc02517065;Hexanoyl-DL-carnitine chloride;Hexanoyl-L-carnitine HCl;3-carboxy-2-(hexanoyloxy)-N,N,N-trimethylpropan-1-aminium | CAS: | 6920-35-0 | MF: | C13H26ClNO4 | MW: | 295.8 | EINECS: | | Product Categories: | Lipid signaling | Mol File: | 6920-35-0.mol | |
| DL-CAPROYLCARNITINE CHLORIDE Chemical Properties |
Melting point | 156-158°C | storage temp. | −20°C | solubility | Methanol (Slightly), Water (Slightly) | form | Solid | color | White to Off-White | Water Solubility | Soluble to 100 mM in water | Stability: | Hygroscopic |
Hazard Codes | Xn | Risk Statements | 22-43 | Safety Statements | 36/37 | WGK Germany | 2 |
| DL-CAPROYLCARNITINE CHLORIDE Usage And Synthesis |
Uses | (±)-Hexanoylcarnitine Chloride acts as a potential absorption-enhancing agents when used in drugs that are poorly absorbed, particularly in the gastrointestinal track. | Biological Activity | (±)-hexanoylcarnitine chloride is an agonist for cholinergic and a homolog of acetylcarnitine chloride (cat no. b6273).acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-hexanoylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3]. |
| DL-CAPROYLCARNITINE CHLORIDE Preparation Products And Raw materials |
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