- β-Elemonic Acid
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- $32.00
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2026-07-27
- CAS:28282-25-9
- Purity: 99.61%
- Supply Ability: 10g
- β-Elemonic Acid
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2026-06-30
- CAS:28282-25-9
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kgs
- β-Elemonic acid
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2023-02-24
- CAS:28282-25-9
- Min. Order: 20mg
- Purity: ≥98%(HPLC)
- Supply Ability: 100 g
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| Product Name: | β-Elemonic Acid | | Synonyms: | Beta-EleMonic;3-OXOTIRUCALLA-8,24-DIEN-21-OIC ACID;β-deMonic acid;(13α,14β,17α,20S)-3-Oxolanosta-8,24-dien-21-oic acid;B-ELEMONIC ACID;(13α,14β,17α,20S)-3-Oxo-5α-lanosta-8,24-dien-21-oic acid;(20S)-3-Oxoeupha-8,24-diene-21-oic acid;3-Oxo-5α-tirucalla-8,24-dien-21-oic acid | | CAS: | 28282-25-9 | | MF: | C30H46O3 | | MW: | 454.69 | | EINECS: | 300-005-5 | | Product Categories: | Triterpenoids;Tri-Terpenoids;reagent;standard substance | | Mol File: | 28282-25-9.mol |  |
| | β-Elemonic Acid Chemical Properties |
| Melting point | 224-225°C | | Boiling point | 565.2±50.0 °C(Predicted) | | density | 1.07 | | storage temp. | 2-8°C | | solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml | | form | A crystalline solid | | pka | 4.65±0.10(Predicted) | | color | White to off-white | | InChIKey | XLPAINGDLCDYQV-XUWOXAENSA-N | | SMILES | C\C(C)=C\CC[C@@H]([C@@H]1CC[C@]2(C)C3=C(CC[C@@]12C)[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC3)C(O)=O |
| WGK Germany | WGK 3 | | Storage Class | 13 - Non Combustible Solids |
| | β-Elemonic Acid Usage And Synthesis |
| Description | β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 µM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 µM) in vitro. | | Uses | beta-Elemonic acid is found in herbs and spices. beta-Elemonic acid is a constituent of elemi resin. beta-Elemonic acid is a flavouring agent. | | Description | β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 μM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 μM) in vitro. | | Chemical Properties | White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from frankincense. | | Uses | β-Elemonic Acid inhibits cell proliferation of human lung adenocarcinoma A549 cells and role of MAPK, ROS activation and glutathione depletion. Elemonic acid is also a Pin1 inhibitors. | | IC 50 | COX-2 | | References | [1] ATTA-UR RAHMAN. Bioactive Constituents from Boswellia papyrifera[J]. Journal of Natural Products , 2005, 68 2: 189-193. DOI: 10.1021/np040142x
[2] TSU-TUAN WU. β-Elemonic acid inhibits the cell proliferation of human lung adenocarcinoma A549 cells: The role of MAPK, ROS activation and glutathione depletion.[J]. Oncology reports, 2016, 16 1: 227-234. DOI: 10.3892/or.2015.4368 |
| | β-Elemonic Acid Preparation Products And Raw materials |
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