| Company Name: |
Shanghai Keepontech Co.,Ltd
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| Tel: |
021-54849683 13601642561 |
| Email: |
sales@keepontech.com |
| Products Intro: |
Product Name:2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE
CAS:26493-11-8
Purity:95% Package:5g;10g;25g;100g Remarks:in stock
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| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-164-7117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:2-Amino-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one
CAS:26493-11-8
Purity:97% Package:100mg;250mg;1g;5g Remarks:BD234261
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| | 2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Basic information |
| Product Name: | 2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE | | Synonyms: | 2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE;2-amino-6,7-dihydro-5H-[1,3]thiazolo[5,4-c]pyridin-4-one;Thiazolo[5,4-c]pyridin-4(5H)-one, 2-amino-6,7-dihydro-;2-Amino-5,6,7,7a-tetrahydro-3aH-thiazolo[5,4-c]pyridin-4-one | | CAS: | 26493-11-8 | | MF: | C6H7N3OS | | MW: | 169.2 | | EINECS: | | | Product Categories: | | | Mol File: | 26493-11-8.mol | ![2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Structure](CAS2/GIF/26493-11-8.gif) |
| | 2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Chemical Properties |
| Boiling point | 559.4±39.0 °C(Predicted) | | density | 1.487±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 13.47±0.20(Predicted) | | Appearance | White to off-white Solid |
| | 2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Usage And Synthesis |
| Synthesis | Step i: Deprotection reaction of tert-butyl 2-amino-4-oxo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
To a 50 mL round bottom flask was added tert-butyl 2-amino-4-oxo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate (0.7 g, 0.0026 mol) and 1,4-dioxane (10 mL). Subsequently, a 1,4-dioxane solution of 4 M hydrochloric acid (10 mL) was added to the same flask. The reaction mixture was stirred at room temperature for 3 hours. After completion of the reaction, the volatile solvent was removed by distillation under reduced pressure to give the crude product. The solid was washed with ether to afford purified 2-amino-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one (0.4 g, 96% yield).LC-MS analysis showed the molecular ion peak of the target compound as 169.9 [M + H]+. | | References | [1] Patent: WO2015/101928, 2015, A1. Location in patent: Page/Page column 66; 67
[2] Patent: WO2011/73339, 2011, A1. Location in patent: Page/Page column 42 |
| | 2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Preparation Products And Raw materials |
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