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DL-3-(4-Fluorophenyl)alanine

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DL-3-(4-Fluorophenyl)alanine manufacturers

DL-3-(4-Fluorophenyl)alanine Basic information
Product Name:DL-3-(4-Fluorophenyl)alanine
Synonyms:rac-(R*)-2-Amino-3-(4-fluorophenyl)-propionic acid;rac-(αR*)-α-Amino-4-fluorobenzenepropionic acid;DL-4-Fluoro-phe-OH;DL-4-Fluorophenylalanine,97%;DL-Phe(p-F);DL-2-Amino-3-(4-fluoro-phenyl)-propionic acid;DL-3-(4-Fluorophenyl;DL-4-F-Phe-OH 4-Fluoro-DL-Phenylalanine
CAS:51-65-0
MF:C9H10FNO2
MW:183.18
EINECS:200-113-7
Product Categories:A - HPeptide Synthesis;Amino Acids;Peptide Synthesis;Phenylalanine Derivatives;Unnatural Amino Acid Derivatives;Modified Amino Acids;Fluorobenzene;Benzenes;amino
Mol File:51-65-0.mol
DL-3-(4-Fluorophenyl)alanine Structure
DL-3-(4-Fluorophenyl)alanine Chemical Properties
Melting point 253-255 °C (dec.)(lit.)
density 1.1939 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pkapK1:2.13(+1);pK2:9.05(0) (25°C)
Boiling point 313.3±32.0 °C(Predicted)
form powder to crystal
color White to Almost white
Optical Rotation0.40°(C=0.01g/ml 1N HCL)
Water Solubility slightly soluble
BRN 29338793
Stability:Stable. Combustible. Incompatible with strong oxidising agents. May be light sensitive.
Major Applicationpeptide synthesis
InChI1S/C9H10FNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
InChIKeyXWHHYOYVRVGJJY-UHFFFAOYSA-N
SMILESNC(Cc1ccc(F)cc1)C(O)=O
CAS DataBase Reference51-65-0(CAS DataBase Reference)
EPA Substance Registry Systemp-Fluorophenylalanine (51-65-0)
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS AY6315000
Hazard Note Harmful
TSCA TSCA listed
PackingGroup III
HS Code 29224999
Storage Class6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard ClassificationsAcute Tox. 2 Oral
Hazardous Substances Data51-65-0(Hazardous Substances Data)
ToxicityLD50 intraperitoneal in mouse: > 1gm/kg
MSDS Information
ProviderLanguage
DL-3-(4-Fluorophenyl)alanine English
SigmaAldrich English
ACROS English
ALFA English
DL-3-(4-Fluorophenyl)alanine Usage And Synthesis
Chemical Propertieswhite powder or flakes
Usespeptide synthesis
DefinitionChEBI: A phenylalanine derivative in which the hydrogen at position 4 on the benzene ring is replaced by a fluoro group.
General DescriptionWhite powder or white shiny flakes.
Air & Water ReactionsInsoluble in water.
Reactivity ProfileDL-3-(4-Fluorophenyl)alanine may be sensitive to exposure to light. A fluorinated amino acid. This is a neutral to slightly acidic material. DL-3-(4-Fluorophenyl)alanine may react as an organic amine or acid, although, its reactivity is moderated considerably by the presence of the other group.
Health HazardSYMPTOMS: DL-3-(4-Fluorophenyl)alanine is a phenylalanine antagonist and may cause inhibition of protein synthesis.
Fire HazardFlash point data for DL-3-(4-Fluorophenyl)alanine are not available; however, DL-3-(4-Fluorophenyl)alanine is probably combustible.
Biochem/physiol ActionsInhibits mitosis and reversibly arrests HeLa cells in G2.
DL-3-(4-Fluorophenyl)alanine Preparation Products And Raw materials
Raw materials4-Fluorobenzaldehyde-->Hippuric acid
Preparation Products4-Fluoro-D-phenylalanine-->L-4-Fluorophenylalanine-->(R)-3-Amino-3-(4-fluoro-phenyl)-propionic acid
Tag:DL-3-(4-Fluorophenyl)alanine(51-65-0) Related Product Information
2-Bromo-DL-Phenylalanine DL-4-Cyanophenylalanine DL-4-Chlorophenylalanine 2-Amino-3-(3-methoxy-phenyl)-propionic acid DL-Penicillamine DL-Phenylalanine DL-BETA-(P-FLUOROPHENYL)ALANINE DL-3,4-Difluorophenylalanine L-4-Fluorophenylalanine FMOC-D-4-Fluorophe Fenfluramine BOC-L-3,4-Difluorophe FMOC-L-4-Fluorophe Fmoc-D-pentafluorophenylalanine 3-Fluoro-D-phenylalanine 2-Fluoro-DL-phenylalanine N-Acetyl-4-fluoro-DL-phenylalanine Boc-p-fluoro-DL-Phe-OH