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| | 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Basic information |
| Product Name: | 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) | | Synonyms: | 2-amino-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one;4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI);4H-Pyrrolo3,2-dpyrimidin-4-one, 2-amino-1,5-dihydro-;9-deazaguanine;2-amino-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one;2-Amino-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one;NSC 344522;2-amino-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one | | CAS: | 65996-58-9 | | MF: | C6H6N4O | | MW: | 150.14 | | EINECS: | | | Product Categories: | Heterocycles;Nucleotides;Heterocyclic Compounds;Bases & Related Reagents;AMINEPRIMARY;PYRIMIDINE | | Mol File: | 65996-58-9.mol | ![4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Structure](CAS/GIF/65996-58-9.gif) |
| | 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Chemical Properties |
| Melting point | >300 °C(Solv: water (7732-18-5)) | | density | 1.87±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | pka | 10.85±0.20(Predicted) | | form | Solid | | color | Beige |
| | 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Usage And Synthesis |
| Description | 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). Inhibitors of PNP are used to control T cell proliferation, particularly in T cell cancers, autoimmune diseases, and tissue transplant rejection. | | Chemical Properties | Beige Solid | | Uses | A nucleoside analog as potent inhibitor of purine nucleoside phosphorylase. |
| | 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) Preparation Products And Raw materials |
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