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BOC Sciences
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Product Name:Napyradiomycin A1
CAS:103106-24-7
Remarks:Napyradiomycin A1 is an antibiotic produced by Chainia rubra MG802-AF1. It has anti-gram-positive ba
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Product Name:Napyradiomycin A1
CAS:103106-24-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Zhejiang Huida Biotech Co., LTD
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0571-89903882 13626641628 |
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| Products Intro: |
Product Name:Napyradiomycin A1
CAS:103106-24-7
Purity:99% HPLC Package:10mg；100mg；1g；10g；100g
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| Company Name: |
Zhejiang Huida Biotech Co., LTD
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| Tel: |
0571-0571-89903882 15990081639 |
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sunshixuan@huidabiotech.com |
| Products Intro: |
Product Name:Napyradiomycin A1
CAS:103106-24-7
Purity:99% HPLC Package:10mg；100mg；1g；10g；100g
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| | napyradiomycin A1 Basic information |
| Product Name: | napyradiomycin A1 | | Synonyms: | napyradiomycin A1;3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione;Napyradiomycin A;WS-9558A;2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)- | | CAS: | 103106-24-7 | | MF: | C25H30Cl2O5 | | MW: | 481.41 | | EINECS: | | | Product Categories: | Antibiotic | | Mol File: | 103106-24-7.mol |  |
| | napyradiomycin A1 Chemical Properties |
| Boiling point | 642.5±55.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble | | form | A solid | | pka | 6.14±0.70(Predicted) |
| HS Code | 29419000 | | Toxicity | mouse,LD50,intraperitoneal,> 250mg/kg (250mg/kg),Journal of Antibiotics. Vol. 39, Pg. 487, 1986. |
| | napyradiomycin A1 Usage And Synthesis |
| Description | Napyradiomycin A1 is a fungal metabolite originally isolated from C. rubra and has diverse biological activities. It is active against S. aureus, M. luteus, B. anthracis, C. bovis, and M. smegmatis (MICs = 1.56-12.5 μg/ml). Napyradiomycin A1 is an estrogen receptor antagonist (IC50 = 4.2 μM in rat uterine homogenates). It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC50s = 20 and 9.7 μM, respectively). | | Uses | Napyradiomycin derivatives have antibacterial and tumor properties. Napyradiomycin A1 is a secondary metabolite isolated from Streptomyces. It is also an antibacterial antibiotic and an inhibitor of mitochondrial complexes I and II. | | Definition | ChEBI: Napyradiomycin A1 is a member of menaquinones. |
| | napyradiomycin A1 Preparation Products And Raw materials |
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