Phosphine-biotin manufacturers
- Phosphine-biotin
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2025-06-07
- CAS:608514-42-7
- Min. Order: 5mg
- Purity: >95.00%
- Supply Ability: 5mg
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| | Phosphine-biotin Basic information |
| Product Name: | Phosphine-biotin | | Synonyms: | Phosphine-biotin;ABJATKZPSPFIQY-CELQPYBTSA-N;Benzoic acid, 2-(diphenylphosphino)-4-[21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1,17-dioxo-6,9,12-trioxa-2,16-diazaheneicos-1-yl]-, methyl ester;Methyl 2-(diphenylphosphaneyl)-4-((15-oxo-19-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10-trioxa-14-azanonadecyl)carbamoyl)benzoate;Methyl 4-[3-[2-[2-[3-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]propoxy]ethoxy]ethoxy]p ropylcarbamoyl]-2-diphenylphosphanylbenzoate | | CAS: | 608514-42-7 | | MF: | C41H53N4O8PS | | MW: | 792.92 | | EINECS: | | | Product Categories: | | | Mol File: | 608514-42-7.mol |  |
| | Phosphine-biotin Chemical Properties |
| solubility | DMSO: 2 mg/ml | | form | A crystalline solid |
| | Phosphine-biotin Usage And Synthesis |
| Description | Phosphine biotin is a labeling reagent that selectively reacts with azido groups on modified proteins through the Staudinger ligation reaction. Modified proteins can be detected using common avidin-based biochemical techniques in whole cells or by blotting experiments following SDS-PAGE. For example, phosphine-biotin has been used successfully in conjunction with DAz-1 or DAz-2 to label and detect sulfenic acid sites in proteins.1,2 | | Uses | Phosphine-biotin is a labeling reagent that selectively reacts with azido groups on modified proteins through the Staudinger ligation reaction[1]. | | References | 1. Seo, Y.H., and Carroll, K.S. Facile synthesis and biological evaluation of a cell-permeable probe to detect redox-regulated proteins Bioorg. Med. Chem. Lett. 19(2),356-359(2009).
2. Reddie, K.G., Seo, Y.H., Muse, W.B., III, et al. A chemical approach for detecting sulfenic acid-modified proteins in living cells Mol. Biosyst. 4(6),521-531(2008). |
| | Phosphine-biotin Preparation Products And Raw materials |
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