| Company Name: |
ChemPep, Inc.
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| Tel: |
+1 (888) 615-9178 / (561) 791-8787 |
| Email: |
service@chempep.com |
| Products Intro: |
Product Name:mPEG8-Propyne
CAS:880081-81-2
Purity:95% Package:1 g, 5 g Remarks:PEGylation Reagents
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mPEG8-Alkyne manufacturers
- Propargyl-PEG9-methane
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- $0.00 / 1g
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2024-03-26
- CAS:880081-81-2
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | mPEG8-Alkyne Basic information |
| Product Name: | mPEG8-Alkyne | | Synonyms: | MPEG8-PROPYNE;mPEG8-Alkyne;mPEG11-Alkyne;m-PEG8-O-alkyne;2,5,8,11,14,17,20,23,26-Nonaoxanonacos-28-yne;m-PEG9-Propargyl;inhibit,m-PEG-8-O-alkyne,PROTAC Linkers,m PEG8 O alkyne,Inhibitor,mPEG8Oalkyne;mPEG8-Propyne/2,5,8,11,14,17,20,23,26-Nonaoxanonacos-28-yne | | CAS: | 880081-81-2 | | MF: | C20H38O9 | | MW: | 422.51 | | EINECS: | | | Product Categories: | | | Mol File: | 880081-81-2.mol |  |
| | mPEG8-Alkyne Chemical Properties |
| Boiling point | 468.8±40.0 °C(Predicted) | | density | 1.057±0.06 g/cm3(Predicted) |
| | mPEG8-Alkyne Usage And Synthesis |
| Biological Activity | m-PEG8-O-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | mPEG8-Alkyne Preparation Products And Raw materials |
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