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Shanghai Hongye Biotechnology Co. Ltd
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sales@glpbio.cn |
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Product Name:15-deoxy-δ12,14-Prostaglandin D2
CAS:85235-11-6
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:15-deoxy-Δ12,14-Prostaglandin D2
CAS:85235-11-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627 |
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customer_service@efebio.com |
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Product Name:15-deoxy-Δ12,14-Prostaglandin D2
CAS:85235-11-6
Purity:95% Package:500μg;1mg;5mg
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| Company Name: |
Cayman Chemical Company
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(800) 364-9897 |
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cayman@caymanchem.com |
| Products Intro: |
Product Name:15-deoxy-Δ12,14-Prostaglandin D2
CAS:85235-11-6
Package:>=95% Remarks:12700
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| | 15-DEOXY-DELTA12,14-PROSTAGLANDIN D2 Basic information |
| Product Name: | 15-DEOXY-DELTA12,14-PROSTAGLANDIN D2 | | Synonyms: | 15-DEOXY-DELTA12,14-PROSTAGLANDIN D2;9ALPHA,HYDROXY-11-OXO-PROSTA-5Z,12E,14E-TRIEN-1-OIC ACID;15-deoxy-Δ12,14-Prostaglandin D2;QUGBPWLPAUHDTI-PLGLXCLHSA-N;Prosta-5,12,14-trien-1-oic acid, 9-hydroxy-11-oxo-, (5Z,9α,12E,14E)-;Prosta-5,12,14-trien-1-oicacid, 9-hydroxy-11-oxo-, (5Z,9a,12E,14E)- | | CAS: | 85235-11-6 | | MF: | C20H30O4 | | MW: | 334.45 | | EINECS: | | | Product Categories: | | | Mol File: | 85235-11-6.mol |  |
| | 15-DEOXY-DELTA12,14-PROSTAGLANDIN D2 Chemical Properties |
| Boiling point | 535.0±50.0 °C(Predicted) | | density | 1.113±0.06 g/cm3(Predicted) | | solubility | DMF: >100 mg/ml (from PGD2); DMSO: >50 mg/ml (from PGD2); Ethanol: >75 mg/ml (from PGD2); PBS pH 7.2: >5 mg/ml (from PGD2) | | pka | 4.75±0.10(Predicted) |
| | 15-DEOXY-DELTA12,14-PROSTAGLANDIN D2 Usage And Synthesis |
| Description | 15-deoxy-Δ12,14-PGD2 is a metabolite of PGD2 . It is an agonist of PGD2 receptor 2 (DP2) that binds DP2 (Ki = 50 nM for the mouse receptor expressed in HEK293 cell membranes) and induces activation of eosinophils (EC50 = 8 nM). It also stimulates the recruitment of steroid receptor coactivator-1 (SRC-1) to peroxisome proliferator-activated receptor γ (PPARγ) and induces PPARγ-mediated transcription in a reporter assay when used at a concentration of 5 μM. 15-deoxy-Δ12,14-PGD2 is cytotoxic to L1210 murine leukemia cells (IC50 = 0.3 μg/ml). It inhibits ADP-induced platelet aggregation (IC50 = 320 ng/ml) less potently than PGD2. |
| | 15-DEOXY-DELTA12,14-PROSTAGLANDIN D2 Preparation Products And Raw materials |
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