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| | 3-Nitro-L-tyrosine Basic information |
| | 3-Nitro-L-tyrosine Chemical Properties |
| Melting point | 233-235 °C (dec.) (lit.) | | alpha | 4 º (c=1, 1N HCl) | | Boiling point | 367.79°C (rough estimate) | | density | 1.4160 (rough estimate) | | refractive index | 1.5373 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Aqueous Acid (Slightly), Water | | form | crystalline | | pka | 2.17±0.20(Predicted) | | color | yellow to green | | Water Solubility | insoluble | | BRN | 2813157 | | CAS DataBase Reference | 621-44-3(CAS DataBase Reference) |
| | 3-Nitro-L-tyrosine Usage And Synthesis |
| Description | Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo. Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions. The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by gas chromatography/mass spectrometry. | | Chemical Properties | ochre-yellow to yellow-green powder | | Uses | 3-Nitro-L-tyrosine is used as an indicator of the formation of peroxynitrite by NO-dependent oxidative damage. | | Uses | A marker for peroxynitrite. Oxidant and cytotoxic agent. | | Definition | ChEBI: 3-nitro-L-tyrosine is a 3-nitrotyrosine comprising L-tyrosine having a nitro group at the 3-position on the phenyl ring. It is a L-tyrosine derivative, a non-proteinogenic L-alpha-amino acid and a 3-nitrotyrosine. It is an enantiomer of a 3-nitro-D-tyrosine. | | Biochem/physiol Actions | Oxidant and cytotoxic agent. |
| | 3-Nitro-L-tyrosine Preparation Products And Raw materials |
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