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| | MET-ENKEPHALIN-ARG-PHE Basic information |
| Product Name: | MET-ENKEPHALIN-ARG-PHE | | Synonyms: | [Met5]enkephalyl-Arg-Phe;L-Tyr-Gly-Gly-L-Phe-L-Met-L-Arg-L-Phe-OH;Tyr-Gly-Gly-Phe-Met-Arg-Phe-OH;Met-Enkephalin-Arg-Phe
MERF;Methionine Enkephalin-Arg-Phe acetate salt hydrate;Tyr-Gly-Gly-Phe-Arg-Arg-Phe;Met-Enkephalin-RF;arg(6)-phe(7)-enkephalin-me | | CAS: | 73024-95-0 | | MF: | C42H56N10O9S | | MW: | 877.02 | | EINECS: | 000-000-0 | | Product Categories: | | | Mol File: | 73024-95-0.mol |  |
| | MET-ENKEPHALIN-ARG-PHE Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) | | storage temp. | -15°C | | pka | 3.49±0.10(Predicted) | | Sequence | Tyr-Gly-Gly-Phe-Met-Arg-Phe |
| | MET-ENKEPHALIN-ARG-PHE Usage And Synthesis |
| Uses | Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity[1]. | | Definition | ChEBI: Met-enkephalin-Arg-Phe is an organic molecular entity. | | in vivo | Met-Enkephalin-Arg-Phe (10-100 nmol/mouse; i.c.v.; once) shows analgesic activity in mice[1]. | Animal Model: | Male Swiss Webster mice[1] | | Dosage: | 10-100 nmol/mouse | | Administration: | Intracerebralventricular injection, once | | Result: | Produced a dose-related inhibition of the tail-flick response. The effects peaked at 2-4 min and were dissipated by 10 min. The EC50 was 38.5 nmol/mouse. |
| | References | [1] Inturrisi CE, et al. Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7. Proc Natl Acad Sci U S A. 1980 Sep;77(9):5512-4. DOI:10.1073/pnas.77.9.5512 |
| | MET-ENKEPHALIN-ARG-PHE Preparation Products And Raw materials |
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