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7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one

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Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:Bifeprunox
CAS:350992-10-8
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:Bifeprunox
CAS:350992-10-8
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CAS:350992-10-8
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Products Intro: Product Name:7-[4-[(3-phenylphenyl)methyl]-1-piperazinyl]-3H-1,3-benzoxazol-2-one
CAS:350992-10-8
Purity:0.97 Package:mgs,gs,kgs Remarks:A822533
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CAS:350992-10-8
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7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one manufacturers

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  • 2025-07-23
  • CAS:350992-10-8
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  • Bifeprunox
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  • $2500.00 / 100mg
  • 2025-07-18
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7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one Basic information
Product Name:7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one
Synonyms:7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one;Bifeprunox;7-(4-([1,1,-biphenyl]-3-ylmethyl)piperazin-1-yl)benzo[d]oxazol-2(3H)-one;7-[4-[(3-phenylphenyl)methyl]-1-piperazinyl]-3H-1,3-benzoxazol-2-one;2(3H)-Benzoxazolone, 7-[4-([1,1'-biphenyl]-3-ylmethyl)-1-piperazinyl]-
CAS:350992-10-8
MF:C24H23N3O2
MW:385.46
EINECS:
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Mol File:350992-10-8.mol
7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one Structure
7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one Chemical Properties
Safety Information
MSDS Information
7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one Usage And Synthesis
UsesAcute schizophrenia.
DefinitionChEBI: Bifeprunox is a member of biphenyls.
in vivo

Bifeprunox (0.001-2.5 mg/kg) reduces marble burying in mice[2].
Bifeprunox (4-250 μg/kg) influences nicotine-seeking behaviour in response to drug-associated stimuli in rats[3].

Animal Model:Male NMRI mice (weighing 20-22 g)[2]
Dosage:0.001, 0.0025, 0.01, 0.04, 0.16, 0.63, and 2.5 mg/kg
Administration:I.p.
Result:Reduced marble burying. Potently active from 0.0025 mg/kg.
Animal Model:Na?ve male Wistar rats (weighing 250-275 g)[3]
Dosage:4, 16, 64 and 250 μg/kg
Administration:Injected s.c. 30 minutes before testing
Result:4-16 μg/kg dose-dependently attenuated the responsereinstating effects of nicotine-associated cues. Higher doses (64-250 μg/kg, s.c.) reduced spontaneous locomotor activity and suppressed operant responding induced by sucrose-associated cues and by the primary reinforcing properties of nicotine or sucrose.
IC 505-HT1A Receptor: 7.19 (pKi, cortex); D2 Receptor: 8.83 (pKi, striatum); 5-HT1A Receptor: 6.37 (pEC50, hippocampus)
7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one Preparation Products And Raw materials
Tag:7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one(350992-10-8) Related Product Information
2(3H)-Benzoxazolone,7-amino-(9CI) BIFEPRUNOX MESYLATE 7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one
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