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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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| Products Intro: |
Product Name:Indicine N-Oxide
CAS:41708-76-3
Package:0.5Mg,5Mg
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| Company Name: |
Biyu Biotechnology (Shanghai) Co., ltd
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021-26018599 |
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| Products Intro: |
Product Name:Indicin-N-oxid
CAS:41708-76-3
Purity:>96.0 % Package:10mg,50mg,100mg,500mg,or as request Remarks:BY70171
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| Company Name: |
EMMX Biotechnology LLC
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888-539-0666 |
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info@emmx.com |
| Products Intro: |
Product Name:Indicine N-oxide
CAS:41708-76-3
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
Chengdu Push Bio-Technology Co., Ltd.
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028-85370565-229 18080489829 |
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3004654993@qq.com |
| Products Intro: |
Product Name:IndicineN-oxide
CAS:41708-76-3
Purity:95% Package:10mg
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| | indicine-N-oxide Basic information |
| Product Name: | indicine-N-oxide | | Synonyms: | indicine-N-oxide;Indicin-N-oxid;DNAWGBOKUFFVMB-PZIGJSDBSA-N;Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aS)-2,3,5,7a-tetrahydro-1-hydroxy-4-oxido-1H-pyrrolizin-7-yl]methyl ester, (2R,3S)-;(7R,8R)-7-hydroxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl (2R)-2-hydroxy-2-[(1S)-1-hydroxyethyl]-3-methylbutanoate;(+)-Indicine N-oxide;NSC132319 | | CAS: | 41708-76-3 | | MF: | C15H25NO6 | | MW: | 315.36 | | EINECS: | | | Product Categories: | | | Mol File: | 41708-76-3.mol |  |
| | indicine-N-oxide Chemical Properties |
| Melting point | 130.5°C (rough estimate) | | Boiling point | 454.91°C (rough estimate) | | density | 1.1359 (rough estimate) | | refractive index | 1.5000 (estimate) | | pka | 12.54±0.29(Predicted) |
| RIDADR | 1544 | | HazardClass | 6.1(b) | | PackingGroup | III |
| | indicine-N-oxide Usage And Synthesis |
| Description | Heliotropiurn indicurn also contains this base which has the structure given above
based upon comparison with the preceding alkaloid. The base has proved to be
highly active against transplanted neoplasts, Walker-256 carcinosarcoma,
melanoma B-16, leukaemia L-12l 0, leukaemia P-388 and leukaemia P-1534 in
mice and rats, giving up to 91 per cent inhibition of transplanted growth at a
daily dosage of 200 mgm. per kilo. | | Uses | Indicine N-oxide is a pyrrolizidine alkaloid that is isolated from Heliotropium indicum, one of the most widely used herbs in India. Indicine N-oxide exhibits antitumour and antimitotic activity in humans, and has subsequently undergone Phase I & II trials in adults and children with leukemia and solid tumours. | | References | Rao, McBride., U.S. Patent, 3,717,710 February 20,1973 |
| | indicine-N-oxide Preparation Products And Raw materials |
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