Monomethyl succinate

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CAS:77341-67-4
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CAS:77341-67-4
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Products Intro: Product Name:4-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxy-4-oxobutanoic acid
CAS:77341-67-4
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Products Intro: Product Name:4-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxy-4-oxobutanoic acid
CAS:77341-67-4
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  • Monomethyl succinate
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  • 2025-06-20
  • CAS:77341-67-4
  • Min. Order: 1kg
  • Purity: 99.00%
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  • Monomethyl succinate
  •  Monomethyl succinate pictures
  • $0.00 / 1kg
  • 2024-07-22
  • CAS:77341-67-4
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10ton
Monomethyl succinate Basic information
Product Name:Monomethyl succinate
Synonyms:MONO-MENTHYLSUCCINATE;4-(((1R,2S,5R)-2-Isopropyl-5-Methylcyclohexyl)oxy)-4-oxobutanoic acid;Butanedioic acid mono-(5-methyl-2-isopropyl-cyclohexyl) ester;Monomethyl succinate;Mononmethyl succinate;4-[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]oxy-4-oxobutanoic acid;(-)-MenthylSuccinate>;Butanedioic acid, 1-[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl] ester
CAS:77341-67-4
MF:C14H24O4
MW:256.34
EINECS:426-890-4
Product Categories:
Mol File:77341-67-4.mol
Monomethyl succinate Structure
Monomethyl succinate Chemical Properties
Melting point 62.0 to 66.0 °C
Boiling point 374.3±25.0 °C(Predicted)
density 1.06±0.1 g/cm3(Predicted)
FEMA 3810 | MONO-MENTHYL SUCCINATE
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
pka4.42±0.17(Predicted)
color White to Almost white
Odorat 100.00 %. odorless
Odor Typeodorless
JECFA Number447
LogP4.35
EPA Substance Registry SystemButanedioic acid, 1-[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl] ester (77341-67-4)
Safety Information
HS Code 2917.19.7050
MSDS Information
Monomethyl succinate Usage And Synthesis
Chemical Propertiesmono-Menthyl succinate has a mint, cooling taste.
UsesMono-methyl Succinate is one of the substances used in the study of lactobacillus plantarum culture supernatants with potential pro-heating and anti-pathogenic properties in skin chronic wounds
Aroma threshold valuesAroma characteristics at 1.0%: little or no apparent aroma.
Taste threshold valuesThreshold in water: 40 ppm. Taste characteristics at 100 ppm: lingering cooling with a slightly oily mouthfeel.
Synthesis Reference(s)The Journal of Organic Chemistry, 51, p. 2039, 1986 DOI: 10.1021/jo00361a019
Synthesis
Succinic anhydride

108-30-5

L-Menthol

2216-51-5

Monomethyl succinate

77341-67-4

Synthesis Example 1: Synthesis of 1-menthyl-(1-menthoxyethyl) succinate Synthesis of Compound 1: To a 100 mL autoclave, 10.00 g (63.99 mmol) of L-menthol and 6.40 g (63.96 mmol) of succinic anhydride were added, and the air in the autoclave was replaced with nitrogen. Subsequently, the mixture was stirred at 110°C for 8 hours. After completion of the reaction, it was cooled to room temperature and 100 mL of hexane was added to the reaction mixture. The precipitated crystals were filtered and the hexane phase of the filtrate was concentrated to give 16.61 g of 1-menthylsuccinic acid with purity >99.9%.

References[1] Patent: US2011/81393, 2011, A1. Location in patent: Page/Page column 10
[2] Molecules, 2005, vol. 10, # 1, p. 81 - 97
[3] Molecular Crystals and Liquid Crystals, 2015, vol. 609, # 1, p. 31 - 39
[4] Patent: US2009/28803, 2009, A1
Monomethyl succinate Preparation Products And Raw materials
Raw materialsSuccinic anhydride-->MENTHOL-->L-Menthol
Tag:Monomethyl succinate(77341-67-4) Related Product Information
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