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Methylparaben Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:Methylparaben
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:99-76-3
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Products Intro: Product Name:Methylparaben
Company Name: Hubei XinRunde Chemical Co., Ltd.
Tel: +8615102730682; +8618874586545
Products Intro: Product Name:Methylparaben
Purity:99% Package:100g/ bag, 2 kg/ bag, 25kg/ carton or as required Remarks:white crystalline powder
Company Name: Anhui Royal Chemical Co., Ltd.
Tel: +86-025-86736275
Products Intro: Product Name:Methyl 4-hydroxybenzoate
Purity:99.00% Package:25kg/drum;200kg/drum

Lastest Price from Methylparaben manufacturers

  • Methylparaben
  • US $1.00 / KG
  • 2018-08-21
  • CAS:99-76-3
  • Min. Order: 1G
  • Purity: 98%
  • Supply Ability: 100KG
  • Methylparaben
  • US $110.00 / KG
  • 2018-07-27
  • CAS:99-76-3
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 1000kg
Methylparaben Basic information
Content analysis Toxicity Utilization limitation Chemical properties Application Preparation Category Toxic grading Acute toxicity Flammability hazard characteristics Storage Extinguishing agent
Product Name:Methylparaben
Product Categories:API;Other APIs;Aromatic Esters;Antioxidant;Biochemistry;Cosmetics;Color Former & Related Compounds;Developer;Functional Materials;Aromatics
Mol File:99-76-3.mol
Methylparaben Structure
Methylparaben Chemical Properties
Melting point 125-128 °C(lit.)
Boiling point 298.6 °C
density 1,46g/cm
refractive index 1.4447 (estimate)
Fp 280°C
storage temp. 0-6°C
solubility ethanol: soluble0.1M, clear, colorless
form Crystalline Powder
pkapKa 8.15(H2O,t =20.0) (Uncertain)
color White to almost white
Water Solubility Slightly soluble in water.
FreezingPoint 131℃
Merck 14,6107
BRN 509801
Stability:Stable. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference99-76-3(CAS DataBase Reference)
NIST Chemistry ReferenceBenzoic acid, 4-hydroxy-, methyl ester(99-76-3)
EPA Substance Registry SystemBenzoic acid, 4-hydroxy-, methyl ester(99-76-3)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-20/21/22-36
Safety Statements 26-36-24/25-39
WGK Germany 1
RTECS DH2450000
HS Code 29182930
Hazardous Substances Data99-76-3(Hazardous Substances Data)
MSDS Information
4-Hydroxybenzoic acid methyl ester English
SigmaAldrich English
ACROS English
ALFA English
Methylparaben Usage And Synthesis
Content analysisMethod one: determinate according to the content analysis method in "butyl p-hydroxybenzoate (07002)". Per mL 1 mol/L sodium hydroxide is equivalent to the product (C8H8O3) 152.2mg.
Method two: Take 0.1 g (accurate to 1 mg) of the sample previously dried on silica gel for 5 h and move into a 300 ml flask with a glass plug. Plus l mol/L sodium hydroxide 10ml, heated in the water bath for 15min. After cooling, add 0.1mol/L potassium bromate 0.00ml, potassium bromide 5.0g and l mol/L hydrochloric acid 30ml. Put 15min in the dark room after sealing. Add potassium iodide 1 g, shake the flask vigorously, with 0.1mol/L sodium thiosulfate titration, with starch test solution (TS-235) as an indicator. Per ml 0.1mol/L potassium bromate is equivalent to the product (C8H8O3) 25.36mg.
ToxicityADI 0~10mg/kg(FAO/WHO,2001).
LD503000mg/kg(Dog, mouth)
Utilization limitationFAO/WHO (1984): Jam, jelly, 1000mg/kg (single or with benzoate, sorbic acid and potassium sorbate).
EEC(1990,mg/kg): For use in pigment solutions, flavor syrups, coffee extracts, frozen drinks, fruit, glucose and soft drinks, pickled fish, salad, sauce, snack food, concentrated soup and so on, limited to GMP; Beer 70; Snack cereals and soup concentrate 175, the same as "07018 p-hydroxybenzoate".
HACSG is listed as a restricted list.
Chemical propertiesWhite needle crystal; Slightly soluble in water, easily soluble in ethanol, ether, acetone and other organic solvents.
  • Antioxidants.
  • Antimicrobial agents for medicine and organic synthesis.
  • Anti-mildew in food, cosmetics and pharmaceutical industries.
  • As a preservative antiseptic agents in the pharmaceutical industry, also for organic synthesis and food, spices, film and other preservative additives.
  • Similar products produced by similar production methods, like ethyl p-hydroxybenzoate (paraben B) and propyl p-hydroxybenzoate (Nepalese c), are also disinfectant preservatives.The products are irritating to the skin.
PreparationThe drug is esterified with p-hydroxybenzoic acid and methanol. The p-hydroxybenzoic acid was added to excess methanol to dissolve, stirring and adding concentrated sulfuric acid slowly. After heating and refluxing 10h, pour into the water to precipitate crystallization, then washed with water, sodium carbonate solution and water, finally obtain the crude product. Recrystallize from water or 25% ethanol to obtain finished product. The yield was 85%. Raw material consumption (kg/t): p-hydroxybenzoic acid 1200, methanol 1000.
CategoryToxic Chemicals
Toxic gradingModerate toxicity
Acute toxicityAbdomen-mouse LD50: 960 mg/kg
Flammability hazard characteristicsCombustible, excretes spicy smoke from fireground
StorageVentilated , low temperature and dry warehouse.
Extinguishing agentWater, carbon dioxide, dry powder, sand.
Chemical PropertiesColorless crystals or white, crystallinepowder; odorless or faint characteristic odor; slightburning taste. Soluble in alcohol,ether; slightly soluble in water, benzene, and carbontetrachloride.
UsesIt is used as preservative in foods, beverages and cosmetics.
Usesparabens is one of the most commonly used group of preservatives in the cosmetic, pharmaceutical, and food industries. Parabens provide bacteriostatic and fungistatic activity against a diverse number of organisms, and are considered safe for use in cosmetics, particularly in light of their low sensitizing potential. An evaluation of preservatives for use in leave-on cosmetic preparations lists parabens among the least sensitizing. The range of concentrations used in cosmetics varies between 0.03 and 0.30 percent, depending on the conditions for use and the product to which the paraben is added.
UsesMethylparaben is an antimicrobial agent which is a white free-flowing powder. it is active against yeast and molds over a wide ph range. see parabens.
DefinitionChEBI: A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blu berries.
UsesAs preservative in foods, beverages and cosmetics.
HazardToxic. Use in foods restricted to 0.1%.
Contact allergensThis substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
Purification MethodsFractionally crystallise the ester from its melt, and recrystallise it from *benzene, then from *benzene/MeOH and dry it over CaCl2 in a vacuum desiccator. [Beilstein 10 IV 360.]
Tag:Methylparaben(99-76-3) Related Product Information
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