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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037 |
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Product Name:AM 1172;N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzaMide
CAS:251908-92-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
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| Products Intro: |
Product Name:AM 1172
CAS:251908-92-6
Purity:>=98% by HPLC Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
EMMX Biotechnology LLC
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888-539-0666 |
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info@emmx.com |
| Products Intro: |
Product Name:AM 1172
CAS:251908-92-6
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:AM1172
CAS:251908-92-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Product Name: | AM1172 | | Synonyms: | N-5Z,8Z,11Z,14Z-EICOSATETRAENYL-4-HYDROXY-BENZAMIDE;AM1172;N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzamide;4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide;Benzamide, N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxy- | | CAS: | 251908-92-6 | | MF: | C27H39NO2 | | MW: | 409.6 | | EINECS: | | | Product Categories: | | | Mol File: | 251908-92-6.mol |  |
| | AM1172 Chemical Properties |
| Boiling point | 590.8±50.0 °C(Predicted) | | density | 0.983±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in ethanol | | form | solution in ethanol | | pka | 8.53±0.26(Predicted) | | color | Colorless to light yellow |
| | AM1172 Usage And Synthesis |
| Uses | AM 1172 is a potent and selective inhibitor of anandamide uptake and FAAH. | | Biological Activity | Metabolically stable anandamide uptake inhibitor (IC 50 = 2.1 - 2.5 μ M) and fatty acid amide hydrolase (FAAH) inhibitor (K i = 3.18 μ M). Inhibits N -arachidonylethanolamine (AEA) accumulation (IC 50 = 24 μ M) and hydrolysis (K i = 3 μ M), and inhibits N -palmitoylethanolamine (PEA) hydrolysis (IC 50 = 36 μ M) in cerebellar granule neurons. Also acts as a non-selective cannabinoid receptor partial agonist (EC 50 values are 189 and 271 nM at CB 2 and CB 1 receptors respectively). | | references | 1. fegley d, kathuria s, mercier r, et al. anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor am1172. proceedings of the national academy of sciences of the united states of america. 2004;101(23):8756-8761. |
| | AM1172 Preparation Products And Raw materials |
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