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n-Butyl carbamate

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  • CAS:592-35-8
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  • Purity: 99%
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  • n-Butyl carbamate
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  • 2019-07-06
  • CAS:592-35-8
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n-Butyl carbamate Basic information
Product Name:n-Butyl carbamate
Synonyms:usafel-101;usaffo-1;BUTYL CARBAMATE;CARBAMIC ACID N-BUTYL ESTER;n-Butylcarbamate,98+%;N-BUTYLCARBAMICACID;n-Butyl carbamate,97%;Butyl carbaMate 98%
CAS:592-35-8
MF:C5H11NO2
MW:117.15
EINECS:209-751-0
Product Categories:Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Protected Amines;Pharmaceutical Intermediates;Nitrogen Compounds;Organic Building Blocks;Protected Amines
Mol File:592-35-8.mol
n-Butyl carbamate Structure
n-Butyl carbamate Chemical Properties
Melting point 53-55 °C (lit.)
Boiling point 204 °C
density 0.9308 (estimate)
vapor pressure 2.65hPa at 20℃
refractive index 1.4189 (estimate)
Fp 228 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility SOLUBLE
pka13.52±0.50(Predicted)
form powder to crystal
color White to Almost white
Water Solubility SOLUBLE
LogP2.75 at 25℃
CAS DataBase Reference592-35-8(CAS DataBase Reference)
NIST Chemistry ReferenceButyl carbamate(592-35-8)
EPA Substance Registry SystemCarbamic acid, butyl ester (592-35-8)
Safety Information
Hazard Codes Xn,Xi,F
Risk Statements 22-41-43-36/37/38-10-36-20/21/22
Safety Statements 26-36/37/39-24/25-16-7/9-36/37
WGK Germany 1
RTECS EZ0175000
HS Code 29241990
Hazardous Substances Data592-35-8(Hazardous Substances Data)
MSDS Information
ProviderLanguage
Butyl carbamate English
SigmaAldrich English
ACROS English
n-Butyl carbamate Usage And Synthesis
Chemical PropertiesWHITE FLAKES
Flammability and ExplosibilityNot classified
Safety ProfileA poison via intraperitoneal route. Moderately toxic via subcutaneous route. Experimental teratogenic effects. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. See also CARBAMATES. When heated to decomposition it emits toxic fumes of NOx
Synthesis
Urea

57-13-6

1-Butanol

71-36-3

n-Butyl carbamate

592-35-8

DIBUTYL CARBONATE

542-52-9

GENERAL STEPS: First, the catalyst was prepared by calcining Yb(NO3)3-6H2O in air at 350 °C for 4 hours. Subsequently, 48.0 g of n-butanol, 6.0 g of urea and 0.75 g of the above prepared catalyst were added to an autoclave. The reaction was carried out at 180°C for 6 hours under autogenous pressure (about 8.5 atm). At the end of the reaction, the yields of dibutyl carbonate (DBC) and butyl carbamate (BC) were 43.1% by weight and 12.8% by weight, respectively.

References[1] RSC Advances, 2015, vol. 5, # 25, p. 19534 - 19540
[2] RSC Advances, 2015, vol. 5, # 25, p. 19534 - 19540
[3] Patent: US2010/312001, 2010, A1. Location in patent: Page/Page column 4
[4] Patent: TW2017/31810, 2017, A. Location in patent: Paragraph 0080
n-Butyl carbamate Preparation Products And Raw materials
Raw materialsUrea-->1-Butanol
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