ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Thiophene compounds >Tetrahydrothiophene

Tetrahydrothiophene

Tetrahydrothiophene Suppliers list
Company Name: Shaanxi Didu New Materials Co. Ltd
Tel: +86-89586680 +86-13289823923
Email: 1026@dideu.com
Products Intro: Product Name:Formalin;Tetrahydrothiophene
CAS:110-01-0
Purity:0.99 Package:25KG,200L
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: 15028179902 +8615028179902
Email: sales@hbmojin.com
Products Intro: Product Name:Tetrahydrothiophene
CAS:110-01-0
Purity:99% Package:25KG
Company Name: Hebei Yanxi Chemical Co., Ltd.
Tel: +8617531190177
Email: peter@yan-xi.com
Products Intro: Product Name:Tetrahydrothiophene
CAS:110-01-0
Purity:0.99 Package:1kg;25USD|25kg;20USD|100kg;10USD Remarks:Factory direct sales
Company Name: Hebei Jingbo New Material Technology Co., Ltd
Tel: +8619931165850
Email: admin@hbjingbo.cn
Products Intro: Product Name:Tetrahydrothiophene
CAS:110-01-0
Purity:99% Package:25kg;6USD
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:tetrahydrothiophene
CAS:110-01-0
Purity:99% Package:25KG;5KG;1KG

Tetrahydrothiophene manufacturers

  • Tetrahydrothiophene
  • Tetrahydrothiophene pictures
  • $6.00 / 25kg
  • 2023-12-25
  • CAS:110-01-0
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 200000
  • Tetrahydrothiophene
  • Tetrahydrothiophene pictures
  • $25.00 / 1kg
  • 2023-11-21
  • CAS:110-01-0
  • Min. Order: 1kg
  • Purity: 0.99
  • Supply Ability: 10 tons
  • Tetrahydrothiophene
  • Tetrahydrothiophene pictures
  • $0.00 / 1kg
  • 2023-11-01
  • CAS:110-01-0
  • Min. Order: 0.10000000149011612kg
  • Purity: 99.0%min
  • Supply Ability: 20000kg

Related articles

  • Synthesis of Tetrahydrothiophene
  • Tetrahydrothiophene is a five-membered, fully saturated, sulfur heterocycle comprised of four sp3-hybridized carbon atoms and ....
  • Jan 27,2022
Tetrahydrothiophene Basic information
Product Name:Tetrahydrothiophene
Synonyms:TETRAHYDROTHIOPHENE, 1000MG, NEAT;thiophane,tetrahydrothiophene,tetramethylenesulfide,thiolane;Tetramethylene sulfide, Thiolane, Thiophane;Tetrahydrothiophene,98%;Tetrahydrothiophene,Tetramethylene sulfide, Thiolane, Thiophane,;Tetrahydrothiophene (THT);Tetrahydrothiophene, 98% 25GR;Tetrahydrothiophene, 98% 500GR
CAS:110-01-0
MF:C4H8S
MW:88.17
EINECS:203-728-9
Product Categories:Building Blocks;C4 to C6;Chemical Synthesis;Heterocyclic Building Blocks;Thiophenes
Mol File:110-01-0.mol
Tetrahydrothiophene Structure
Tetrahydrothiophene Chemical Properties
Melting point -96 °C (lit.)
Boiling point 119 °C (lit.)
density 1 g/mL at 25 °C (lit.)
vapor pressure 18 mm Hg ( 25 °C)
refractive index n20/D 1.504(lit.)
Fp 55 °F
storage temp. Store below +30°C.
solubility immiscible
form liquid
Specific Gravity1.002 (20/4℃)
color Colorless to Almost colorless
OdorSmells of rotting eggs
PH7 (H2O, 20℃)
explosive limit1.1-12.1%(V)
Odor Threshold0.00062ppm
Odor Typesulfurous
Water Solubility immiscible
Merck 14,9218
BRN 102392
Dielectric constant8.6099999999999994
Stability:Highly flammable. Vapour-air mixtures explosive in some proportions; note low flash point and fairly wide explosion limit range. Heavier than air, so potentially explosive mixtures may travel considerable distances to source of ignition.
LogP1.8 at 20℃
CAS DataBase Reference110-01-0(CAS DataBase Reference)
NIST Chemistry ReferenceThiophene, tetrahydro-(110-01-0)
EPA Substance Registry SystemTetrahydrothiophene (110-01-0)
Safety Information
Hazard Codes F,Xn
Risk Statements 11-20/21/22-36/38-52/53
Safety Statements 16-23-36/37-61
RIDADR UN 2412 3/PG 2
WGK Germany 2
RTECS XN0370000
Autoignition Temperature202 °C
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29349990
Hazardous Substances Data110-01-0(Hazardous Substances Data)
ToxicityLD50 by inhalation in mice: 26.7 mg/l (Carlucci)
MSDS Information
ProviderLanguage
Thiacyclopentane English
SigmaAldrich English
ACROS English
ALFA English
Tetrahydrothiophene Usage And Synthesis
Chemical PropertiesTetrahydrothiophene is cyclic thioalkane, namely, saturated analog of thiophene. It is a colorless transparent volatile liquid, insoluble in water, miscible in ethanol, ether, benzene, acetone. It has a strong unpleasant odor, is stable and not easily emitted, and can be smelled in the air at 0.01PPm. It is not corrosive to gas equipment, transportation pipeline gaskets and other materials, and does not produce habitual blunting of the human sense of smell, so it is used as an odorant in LPG and natural gas, outlawing the original use of ethyl mercaptan and other odor-assigning agents.
UsesTetrahydrothiophene is a solvent and a fuel gas odorant used in fire safety stench warning systems in underground mines. Tetrahydrothiophene was also used as an organocatalyst for the reaction between enynediones and benzoic acid to afford highly substituted furfuryl alcohol benzoates.
UsesTetrahydrothiophene is used as pharmaceutical and agrochemical intermediates.
PreparationTetrahydrothiophene is prepared by the reaction of hydrogen sulfide and furan in the vapor phase at 400°C. This vapor-phase reaction is catalyzed by alumina(Al2O3) and other heterogenous acid catalysts.
DefinitionChEBI: Tetrahydrothiophene is a saturated organic heteromonocyclic parent and a member of tetrahydrothiophenes.
General DescriptionA water-white liquid. About the same density as water and insoluble in water. Flash point near 20°F. Vapors heavier than air. Used as a solvent and to make other chemicals.
Air & Water ReactionsHighly flammable. Insoluble in water.
Reactivity ProfileOrganosulfides, such as Tetrahydrothiophene, are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Slow addition of hydrogen peroxide to the thiophene resulted in explosions on three occasions, Chem. Eng. News, 1974, 52(39), 3.
Health HazardMay cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire HazardHIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Safety ProfileMildly toxic by inhalation. Flammable liquid. Potentially explosive reaction with hydrogen peroxide. When heated to decomposition it emits toxic fumes of SOx.
Purification MethodsThe crude material is purified by crystallisation of the mercuric chloride complex to a constant melting point. It is then regenerated, washed, dried, and fractionally distilled. [Whitehead et al. J Am Chem Soc 73 3632 1951.] It has been dried over Na2SO4 and distilled in a vacuum [Roberts & Friend J Am Chem Soc 108 7204 1986]. [Beilstein 17 I 5, 17 II 15, 17 III/IV 34, 17/1 V 36.]
Tag:Tetrahydrothiophene(110-01-0) Related Product Information
4,5,6,7-Tetrahydrothieno[3,2-c]pyridine D-BIOTIN P-NITROPHENYL ESTER Citiolone 3-METHYLAMINO-N-NITROSOSULFOLANE AKOS BBS-00004892 D-biotin-d-sulfoxide 3,4-DIBROMOSULFOLANE 3-SULFOLANYL ETHER 3-METHYLSULFOLANE 3,4-DICHLOROSULFOLANE 3-[[(9,10-Dihydro-9,10-dioxo-4-hydroxyanthracen)-1-yl]amino]tetrahydrothiophene 1,1-dioxide AKOS BBS-00005046 POLYTHIOPHENE CYCLOBUTANE AKOS BBS-00005153 2-METHYL TETRAHYDROTHIOPHENE-3-ONE Tetrahydrothiophene-2-one 3-CHLORO-4-HYDROXYTETRAHYDROTHIOPHENE-1,1-DIOXIDE