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D-2-Phenylglycine

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Products Intro: Product Name:D-2-Phenylglycine
CAS:875-74-1
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CAS:875-74-1
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CAS:875-74-1
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Products Intro: Product Name:ALPHA-AMINOPHENYLACETIC ACID
CAS:875-74-1
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D-2-Phenylglycine manufacturers

  • H-D-Phg-OH
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  • $0.00/ kg
  • 2024-04-26
  • CAS:875-74-1
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  • D-2-Phenylglycine
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  • CAS:875-74-1
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D-2-Phenylglycine Basic information
Description Storage
Product Name:D-2-Phenylglycine
Synonyms:.alpha.-amino-,(R)-Benzeneaceticacid;Benzeneacetic acid, alpha-amino-, (R)-;Benzeneaceticacid,alpha-amino-,(R)-;D-(-)-2-Phenylglycine,99%;(R)-(-)-ALPHA-AMINOPHENYLACETIC ACID FOR RESOLUTION OF RACEMATES;D(-)-alpha-Aminophenylacetic;D-a-a(1,4-cyclohexadienyl)Glyc;Benzeneacetic acid, .alpha.-amino-, (.alpha.R)-
CAS:875-74-1
MF:C8H9NO2
MW:151.16
EINECS:212-876-3
Product Categories:pharmaceutical;Antidote / Antibiotic / Antimicrobial;Amino Acids;Phenylglycine [Phg];Unusual Amino Acids;GLYCINESCAFFOLD;Pharmaceutical Intermediates;Amino ACIDS SERIES
Mol File:875-74-1.mol
D-2-Phenylglycine Structure
D-2-Phenylglycine Chemical Properties
Melting point 302 °C (dec.)(lit.)
Boiling point 273.17°C (rough estimate)
alpha -156 º (c=1,1N HCl)
density 1.2 g/cm3 (20℃)
vapor pressure 0Pa at 25℃
refractive index -158 ° (C=1, 1mol/L HCl)
Fp 150 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Aqueous Acid (Sparingly), Water (Slightly, Heated)
form Crystalline Powder
pka1.94±0.10(Predicted)
color White
optical activity[α]20/D 155°, c = 1 in 1 M HCl
Water Solubility 0.3g/100mL
Merck 14,7291
BRN 2208676
LogP-1.76 at 20℃
CAS DataBase Reference875-74-1(CAS DataBase Reference)
NIST Chemistry Referenced a-Phenylglycine(875-74-1)
EPA Substance Registry SystemBenzeneacetic acid, .alpha.-amino-, (.alpha.R)- (875-74-1)
Safety Information
Hazard Codes T
Risk Statements 23/24/25-36/37/38-22-20
Safety Statements 22-24/25-45-36/37/39-26-44-28-7-4
WGK Germany 3
TSCA Yes
HS Code 29224995
MSDS Information
ProviderLanguage
D(-)-alpha-Phenylglycine English
SigmaAldrich English
ACROS English
ALFA English
D-2-Phenylglycine Usage And Synthesis
DescriptionL-phenylglycine (Cephalexin EP Impurity A) is a derivative of glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in the spinal cord and an allosteric modulator of NMDA receptors.
StorageStore at room temperature. Store in cool dry place in tightly closed container. Store away from oxidizing agent.
Descriptiond-Phenylglycine is widely used in large quantity as the side chain that makes ampicillin and cephalexin orally acceptable.
Chemical PropertiesWhite crystalline powder
UsesD-(-)-2-Phenylglycine (Cefalexin EP Impurity A) is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
UsesD-(-)-2-Phenylglycine is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA r eceptors.
DefinitionChEBI: The R stereoisomer of alpha-phenylglycine.
Flammability and ExplosibilityNon flammable
SynthesisIndustrially, dphenylglycine has been produced by a conventional resolution method or by kinetic resolution with acylase. Another enzymatic procedure has been developed by Yamada et al. , as shown below.
Synthesis_875-74-1
Tag:D-2-Phenylglycine(875-74-1) Related Product Information
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