(S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺
| 中文名称 | (S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺 |
|---|---|
| 中文同义词 | (S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺;(S)-艾司利卡西平;(S)-LICARBAZEPINE-D4;利卡西;利卡西平杂质6;化合物 T3285L;S-10-单羟基二氢卡马西平;(S)-10-羟基-10,11-二氢-5H-二苯并[[B,F]氮杂-5-甲酰胺 |
| 英文名称 | Eslicarbazepine |
| 英文同义词 | (10S)-10,11-DIHYDRO-10-HYDROXY CARBAMAZEPINE;S-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide,S-MHD;(S)-10-Monohydroxydihydrocarbamazepine;(10S)-;(S)-10-Monohydroxy-10,11-dihydro CarbaMazepine (Eslicarbazepine);5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-, (10S)-;(S)-10-Monohydroxy-dihydro-carbamazepine (Eslicarbazepine);Eslicarbazepine (Synonyms: BIA 2-194) |
| CAS号 | 104746-04-5 |
| 分子式 | C15H14N2O2 |
| 分子量 | 254.28 |
| EINECS号 | |
| 相关类别 | Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Chiral Reagents;Metabolites |
| Mol文件 | 104746-04-5.mol |
| 结构式 | ![(S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺 结构式](CAS/GIF/104746-04-5.gif) |
(S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺 性质
| 熔点 | 188-190°C |
|---|---|
| 沸点 | 431.3±55.0 °C(Predicted) |
| 密度 | 1.336 |
| 储存条件 | -20°C Freezer |
| 溶解度 | 可溶于氯仿（轻微、加热）、甲醇（轻微）、吡啶（轻微） |
| 形态 | 固体 |
| 酸度系数(pKa) | 13.75±0.20(Predicted) |
| 颜色 | 白色至浅黄色 |
| InChI | InChI=1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)/t14-/m0/s1 |
| InChIKey | BMPDWHIDQYTSHX-AWEZNQCLSA-N |
| SMILES | N1(C(N)=O)C2=CC=CC=C2[C@@H](O)CC2=CC=CC=C12 |
Eslicarbazepine (BIA 2-194) 是一种口服抗惊厥试剂，可用于局部癫痫的辅助研究。
Eslicarbazepine is an anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. Eslicarbazepine acetate is a prodrug for eslicarbazepine (S-licarbazepine), which is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/09/15 | HY-114703 | (S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺 Eslicarbazepine | 104746-04-5 | 1 mg | 233元 |
| 2026/09/15 | HY-114703 | (S)-10-羟基二氢-5H-二苯并[B,F]氮杂卓-5-甲酰胺 Eslicarbazepine | 104746-04-5 | 5 mg | 500元 |