紫苏霉素
| 中文名称 | 紫苏霉素 |
|---|---|
| 中文同义词 | 西梭霉素;西索霉素碱;西索米星碱;西苏霉苏;西索米星;紫苏霉素;紫苏霉素/西梭霉素;西索米星/西索霉素 |
| 英文名称 | Sisomicin |
| 英文同义词 | O-3-deoxy-4C-methyl-3-(methylamino)--L-arabinopiranozyl-(1-6)-O[2,6-diamino-2,3,4,6-tetradeooxy-a-D-glycerohexy-4-enopiranozyl-(1-4)]-2-deoxy-D-streptamycin;O-3-Deoxy-4-C-methyl-3-(methylamino)--L-arabinopyranosyl-(1-6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(1-4)]-2-deoxy- D-Streptamine;6-O-(4-C-Methyl-3-methylamino-3-deoxy-β-L-arabinopyranosyl)-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-4-hexenopyranosyl)-2-deoxy-D-streptamine;Sisomicin;Sisomicin (C1a oxidation peak);O-3-Deoxy-4-C-Methyl-3-(MethylaMino)-β-L-arabinopyranosyl-(1-6)-O-[2,6-diaMino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1-4)]-2-deoxy- D-StreptaMine;O-3-Deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(1-6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl-(1-4)]-2-deoxy- D-Streptamine;Sch 13475 |
| CAS号 | 32385-11-8 |
| 分子式 | C19H37N5O7 |
| 分子量 | 447.53 |
| EINECS号 | 251-018-2 |
| 相关类别 | 药物标准品;氨基糖苷类抗生素;原料;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol文件 | 32385-11-8.mol |
| 结构式 |  |
紫苏霉素 性质
| 熔点 | 80-93°C |
|---|---|
| 沸点 | 556.56°C (rough estimate) |
| 密度 | 1.2777 (rough estimate) |
| 折射率 | 1.7600 (estimate) |
| 储存条件 | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| 溶解度 | 可溶于酸水溶液（轻微）、DMSO（轻微）、甲醇（轻微）、水（轻微） |
| 形态 | 固体 |
| 酸度系数(pKa) | 13.29±0.70(Predicted) |
| 颜色 | 淡黄色至黄色凝胶至 |
临床用于治疗烧伤感染细菌性肠炎、痢疾及敏感细菌感染引起的炎症等。
用途
用于生产硫酸西索米星或硫酸奈替米星的中间体用途
用于绿脓杆菌、肠杆菌等革兰阴性菌感染用途
用于绿脓杆菌、肠杆菌等革兰氏阴性菌感染。