| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
|
| Tel: |
029-81124267 15229202216 |
| Email: |
1073@dideu.com |
| Products Intro: |
Product Name:tridihexethyl iodide
CAS:125-99-5
Purity:99% Package:25KG
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| | tridihexethyl iodide Basic information |
| | tridihexethyl iodide Chemical Properties |
| Toxicity | LD50 oral in rat: 1100mg/kg |
| | tridihexethyl iodide Usage And Synthesis |
| Originator | Pathilon,Burroughs-Wellcome,US,1955 | | Definition | ChEBI: Tridihexethyl iodide is an organic iodide salt. It contains a tridihexethyl. | | Manufacturing Process | Acetophenone, paraformaldehyde and diethylamine are first reacted to give ω-
diethylaminopropiophenone. That is reacted with cyclohexylmagnesium
bromide to give 3-diethylamino-1-cyclohexyl-1-phenylpropanol-1.
To 1,320 parts of methyl isobutyl ketone is added 570 parts of 3-
diethylamino-1-cyclohexyl-1-phenylpropanol-1 (2 mols) and the mixture is
stirred until solution is complete. Then 500 parts (3.2 molsor 60% excess) of
ethyl iodide are added. After filtration, the filtrate is diluted with an additional
300 parts of methyl isobutyl ketone and the solution is then heated at the
reflux temperature (108°C to 110°C) for 9 hours. After cooling to 0°C, the
precipitated solid material is removed by filtration, washed with isopropyl
acetate and dried. Approximately 777 parts of product is obtained or a yield of 88.6% based on as-is starting material or 92.5% based on real starting
material. | | Therapeutic Function | Anticholinergic |
| | tridihexethyl iodide Preparation Products And Raw materials |
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