β-Nicotinamide adenine dinucleotide NEW

Chemical properties White powder, easy to absorb moisture, aqueous solution is acidic. The solid is stable under dry conditions, the neutral or weakly acidic aqueous solution of this product can be stored for 7 days at room temperature, and the deterioration and decomposition are accelerated in the case of alkali and heat. Specific rotation [α]23D-34.8°(1%, water); Its aqueous solution has maximum absorption at 260nm and 340nm wavelengths. Soluble in water, insoluble in organic solvents such as acetone. It is a necessary coenzyme in the biological body, used in biochemical research, clinical diagnosis, clinical drugs and drug research. Use Nicotinamide adenine dinucleotide is a kind of coenzyme drug. Clinically, it is mainly used for the auxiliary treatment of coronary heart disease, which can improve chest tightness, angina pectoris and other symptoms. The side effects were dry mouth, dizziness, nausea and so on. Uses Participate in energy metabolism and material metabolism in the body, which is conducive to cell repair and renewal. It is used for the treatment of coronary heart disease, myocarditis, leukopenia and so on. Nicotinamide adenine dinucleotide is a coenzyme that transfers protons (more precisely hydrogen ions) and occurs in many metabolic reactions in cells. NADH or Chemicalbook is more accurate NADH+H+ is its reduced form. It can be reduced to carry up to two protons (written NADH+H+). NAD+ is a coenzyme of dehydrogenases, such as ethanol dehydrogenase (ADH), used to oxidize ethanol. It plays an irreplaceable role in glycolysis, gluconeogenesis, tricarboxylic acid cycle and respiratory chain. The intermediate will pass the removed hydrogen to NAD, making it NADH+H+. NADH+H+ will act as a carrier of hydrogen in the respiratory chain through chemical osmotic coupling, synthesis of ATP. In terms of light absorption, NADH+H+ has an absorption peak at 260nm and 340nm, while NAD+ only has an absorption peak at 260nm, which is an important attribute that distinguishes the two. This is also the physical basis for measuring metabolic rate in many metabolic tests. NAD has a light absorption coefficient of 1.78*104L/(mol*cm) at 260nm, while NADH has a light absorption coefficient of 6.2*10³L/(mol*cm) at 340nm.