Product Details
| Product Name: Exemestane | CAS No.: 107868-30-4 |
| EC-No.: 643-090-2 | Min. Order: 1g |
| Purity: 99% | Supply Ability: 500kg |
| Release date: 2021/12/23 |
Product Name: Exemestane
CAS: 107868-30-4
MF: C20H24O2
MW: 296.4
EINECS: 643-090-2
Melting point 155.13°C
Boiling point 453.7±45.0 °C(Predicted)
density 1.13±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: ≥20mg/mL
form powder
color white to off-white
Exemestane is an irreversible steroid aromatase inhibitor. Its structure is similar to that of aromatase’s natural substrate, androstenedione, and acts as a pseudosubstrate. Postmenopausal women’s estrogen is mainly converted from androgen (produced by the adrenal cortex) by aromatase in the surrounding tissue. This drug irreversibly binds with the active site on aromatase to deactivate it, thus dramatically lower estrogen levels in the blood circulation of postmenopausal women. By inhibiting aromatase to lower estrogen levels, it can be used to treat hormone-dependent breast cancer in postmenopausal women.
Exemestane is suitable for treating advanced breast cancer in naturally or artificially postmenopausal women that has not responded well to tamoxifen treatment. It is also suitable for treating estrogen and progesterone receptor positive postmenopausal advanced breast cancer, and it can also be used to treat metastasized breast cancer and as adjuvant therapy for early breast cancer.
Exemestane is suitable for treating advanced breast cancer in naturally or artificially postmenopausal women that has not responded well to tamoxifen treatment. It is also suitable for treating estrogen and progesterone receptor positive postmenopausal advanced breast cancer, and it can also be used to treat metastasized breast cancer and as adjuvant therapy for early breast cancer.
Company Profile Introduction
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD is located in Jiangxia District, Wuhan City, Hubei Province. Main pharmaceutical intermediates, raw materials, food additives, antibiotics raw materials, etc. Wuhan dongkangyuan Technology Co., Ltd. is located in Wuhan, the thoroughfare of nine provinces. It is a high-tech industrial company specializing in the R & D and sales of chemical raw materials in Central China. The company has its own R & D base, equipped with advanced production equipment and high-efficiency precision testing instruments, with a complete, scientific and quality management system. And constantly committed to technological innovation, product innovation and management innovation, with high-tech and excellent innovation quality service has won the trust of University organs, scientific research institutions, pharmaceutical manufacturers, quality inspection departments, environmental protection enterprises, chemical production, agricultural production, food related industries and other industries. In order to ensure that our products in the same industry with super competitiveness. The company has independent import and export operation rights and excellent sales team.
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China- Since: 2013-04-05
- Address: Yuanfen Road community, Wuchang District, Wuhan City
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