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Postion:Product Catalog >API>Circulatory system drugs>Antihypertensive drugs>Irbesartan
Irbesartan
  • Irbesartan
  • Irbesartan
  • Irbesartan
  • Irbesartan
  • Irbesartan

Irbesartan NEW

Price Get Latest Price
Package 1Kg/Bag 25Kg/Bag 100Kg/Bag
Min. Order: 1Kg/Bag
Supply Ability: 20 tons
Update Time: 2024-04-22

Product Details

Product Name: Irbesartan CAS No.: 138402-11-6
EC-No.: 604-078-2 Min. Order: 1Kg/Bag
Purity: EP / USP Supply Ability: 20 tons
Release date: 2024/04/22

Product Information

Product name

Irbesartan

CAS No.

138402-11-6

Molecular Formula

C25H28N6O

Molecular Weight

428.53

Quality Standard

98% up, USP/ EP

Appearance

White to almost white powder


Usage

Function of Irbesartan

Irbesartan is an angiotensin Ⅱ (Angiotensin Ⅱ, Ang Ⅱ) receptor inhibitor, can inhibit the conversion of Ang Ⅰ to Ang Ⅱ, can specifically antagonize the angiotensin converting enzyme 1 receptor (AT1), the antagonism of AT1 is greater than AT28500 Double, by selectively blocking the binding of AngⅡ and AT1 receptors, inhibiting vasoconstriction and the release of aldosterone, resulting in a hypotensive effect. This product does not inhibit angiotensin converting enzyme (ACE), renin, other hormone receptors, nor does it inhibit ion channels related to blood pressure regulation and sodium balance. It is mainly used for the treatment of essential hypertension and type 2 diabetic nephropathy with hypertension.


COA of Irbesartan

ITEMS

STANDARDS

RESULTS

Appearance

White to off-white powder

White powder



Identification

Infrared absorption:

The IR spectrum is consistent with that obtained with the reference


Conforms

The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay

Conforms

Water

NMT 0.5%

0.24%

Limit or Azide

NMT10ppm

Not detected

Heavy metals

NMT0.002%

Conforms

Related compounds

(HPLC)

Compound A NMT0.2%

0.01%

Any other impurity NMT0.1%

0.04%

Total impurity NMT0.5%

0.09

Residual solvents(GC)

Ethanol NMT 5000ppm

2307 ppm

Toluene NMT 890ppm

238 ppm

Dichloromethane NMT3000 ppm

Not detected

N,N-Dimethylformamide NMT880 ppm

Not detected

T-butyl Methyl Ether NMT 5000 ppm

Not detected

Assay

98.0—102.0%

99.2%

Conclusion

The analysis results show that this batch of irbesartan conforms to USP


Company Information

Article illustration




Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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