Ketotifen Fumarate

Product Information
Product Name          Ketotifen Fumarate
Synonyms               Ketotifen Fumarate Salt
CAS No.                  34580-14-8
EINECS No.              252-100-0
Molecular formula     C23H23NO5S
Molecular weight      425.5

Physical Properties
White to brownish yellow crystalline powder, Odorless, taste bitter, slightly soluble in water and ethanol, easily soluble in methanol, very slightly soluble in chloroform and acetone
Melting Point           192℃

Specification
Appearance                        White to brownish yellow crystalline powder
Loss on drying                     ≤0.5%
Sulfate ash                         ≤0.1%
Related substance (HPLC)
   Impurity A                        ≤0.2%
   Impurity G                        ≤0.2%
   Single impurity                  ≤0.1%
   Total impurities                 ≤0.5%
Residual solvents
   Acetone                          ≤5000ppm
   Methanol                         ≤500ppm
Assay                                 99~101.5%

Applications
1) Dermatologist for urticaria, pruritus, eczema, allergic dermatitis and atopic dermatitis, neurodermatitis and other allergic diseases
2) Antihistamines, antiasthmatic, used for prevention and treatment of bronchitis & asthma.