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Postion:Product Catalog >API>Antiallergic drugs>Antihistamines>Promethazine hydrochloride
Promethazine  hydrochloride
  • Promethazine  hydrochloride
  • Promethazine  hydrochloride
  • Promethazine  hydrochloride
  • Promethazine  hydrochloride
  • Promethazine  hydrochloride

Promethazine hydrochloride

Price $1
Package 1G
Min. Order: 1G
Supply Ability: 10000000
Update Time: 2018-10-22

Product Details

Product Name: Promethazine hydrochloride CAS No.: 58-33-3
Min. Order: 1G Purity: 99.5%
Supply Ability: 10000000 Release date: 2018/10/22

Promethazine (hydrochloride)

 

 

DESCRIPTION
Synonyms
  • Diprazin
  • Fellozine
  • Lergigan
  • Phenergan
  • Romergan

Promethazine is a first generation histamine H1 receptor antagonist (Ki = 2.6 nM) whose antihistamine activity has been reported in guinea pigs and mice at ED50 values of 0.43 and 5.9 mg/kg, respectively.1,2 Promethazine can penetrate the CNS, depressing central H1 receptor activity, which may relate to its sedative properties, and can also inhibit muscarinic acetylcholine receptors (Ki = 22 nM).1,2 Furthermore, 32 mg/kg promethazine demonstrates antiemetic effects in ferret models of motion sickness or chemotherapy-induced nausea.

TECHNICAL INFORMATION
Formal Name
N,N,α-trimethyl-10H-phenothiazine-10-ethanamine, monohydrochloride
CAS Number
58-33-3
Synonyms
  • Diprazin
  • Fellozine
  • Lergigan
  • Phenergan
  • Romergan
Molecular Formula
C17H20N2S • HCl
Formula Weight
320.9
Purity
≥95%
Formulation
A crystalline solid
λmax
252, 300 nm
SMILES
CC(N(C)C)CN1C2=C(C=CC=C2)SC3=CC=CC=C31.Cl
InChI Code
InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
InChI Key
XXPDBLUZJRXNNZ-UHFFFAOYSA-N

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Company Profile Introduction

Meihua Biological Technology Co.,Ltd, is a global trading company, has been focusing on developing and manufacturing of advanced fine chemical and multiple intermediates. we are all members devoted to working in the filed for seven years. Rich experience gives us great enlightenments in founding of enterprise Meihua Biological Technology Co.,Ltd ,was established on the ground in 2011, is a collection, production, assay and sales into an integrated trading company in one of professional service and exported enterprise. As a mature manufacture, we have rigorous process flow. All final products come to us only by passing HPLC or GC assay. Through 30 procedures in all, we concentrate on every one gram of quality and every one milliliter of purity to your trust. We customize organic material,biochemical reagents,fine chemicals, pharmaceutical intermediates, OLED intermediates, liquid crystal intermediates and glucosides for customers, with high quality, competitive price, professional service and reliable source, and hundreds of species to choose. Such as 4-MPD/5F-ADB/2F-DCK/BK-EBDP/FUB-AMB/ADBF and so on, and new productions including 4433-77-6(BMK)/13605-48-6(PMK)16648-44-5(Benzeneacetic Acid ) etc. Of course, we support various transportation and safe payment. We are aiming at becoming a leading manufacture and trading company in China, even global. We are looking forward to establishing long-term cooperation relationship with customers in the word. We sincerely welcome to contact with us. For more information, please visit our website at http://www.hbmeihua.cn/

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