Fluoxetine

Price	$1
Package	1KG

Product Details

Product Name: Fluoxetine	CAS No.: 54910-89-3
Min. Order: 1G	Purity: 98%
Supply Ability: 100KG	Release date: 2019/07/06

AD68

Fluoxetine Basic information

Chemical propertis Antidepressant Precautions

Product Name:	Fluoxetine
Synonyms:	(+/-)-n-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine;METHYL-[3-PHENYL-3-(4-TRIFLUOROMETHYLPHENOXY)PROPYL]AMINE;AURORA KA-7692;FLUOXETINE;(+-)-benzenepropanamin;(+)or(-)-n-methyl-3-phenyl-3-(alpha,alpha,alpha-trifluoro-p-tolyl)oxy)prop;(+)or(-)-n-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine;dl-3-(p-trifluoromethylphenoxy)-n-methyl-3-phenylpropylamine
CAS:	54910-89-3
MF:	C17H18F3NO
MW:	309.33
EINECS:	244-296-1
Product Categories:	API;CEFTIN
Mol File:	54910-89-3.mol

Fluoxetine Chemical Properties

CAS DataBase Reference	54910-89-3(CAS DataBase Reference)
NIST Chemistry Reference	Fluoxetine(54910-89-3)

Safety Information

MSDS Information

Provider	Language
(+/-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine	English

Fluoxetine Usage And Synthesis

Chemical propertis	Fluoxetine Hydrochloride: White or white crystalline solids with a melting point of 158.4 to 158.9℃. Soluble in methanol or ethanol, dissolved in acetonitrile, acetone, or chloroform, and slightly soluble in ethyl acetate, dichloromethane, or water(with sonication at pHl.2，4.5，7.0).Almost insoluble in cyclohexane, hexane or toluene. Solubility(mg/m1)：Methanol and ethanol > 100, Acetone, acetonitrile and chloroform 33~100, dichloromethane 5~10, water 1~2, ethyl acetate 2 ~ 2.5, Cyclohexane, hexane and toluene 0.5 ~ 0.67. The maximum solubility in water: 14mg/ml. UV maximum absorption (methanol):227，264，268，275nm (E1cm1%372.0，29.2，29.3，21.5). Acute toxic of LD50 for large rate and small rat (mg/kg): 248, 452 oral administrations.
Antidepressant	Fluoxetine is an antidepressant of the selective serum reabsorption inhibitor (SSRI) type.The drug takes the form of Fluoxetine hydrochloride. Its trade name is "Prozac". The drug was developed by the Eli Lilly and Company. It has been launched into market for sale since the 1990s. This drug is used for the treatment of adult depression, obsessive-compulsive disorder, bulimia nervosa and the panic disorder that has or does not have the phobia of the square. It has good antidepressant effect and is widely used in clinical practice as a first-line antidepressant.The main pharmacological effect is to selectively inhibit the reuptake of 5 hydroxytryptamine (HT), which is released before the synapse of the central nervous system.It is also known as a selective 5- serotonin reuptake inhibitor. For other receptors, such as alpha adrenergic, beta adrenergic, 5- serotonin, and dopamine, fluoxetine had almost no binding force. Fluoxetine is well absorbed from the gastrointestinal tract after oral administration.The plasma concentration is about 6~8 hours, and eating does not affect its bioavailability. About 95% are combined with plasma proteins and are widely distributed.After taking the medicine for several weeks, the steady plasma concentration will be reached.By metabolism of the liver, the active metabolite, norfluoxetine is generated by demethylation. The half-life of fluoxetine is 4-6 days, and norfluoxetine is 4-16 days.It was mainly excreted by kidney. Because it can be secreted to breast milk, it is suggested to be cautious to pregnant women and breast-feeding women.
Precautions	There are a lot of side effects and the common adverse reactions are: systemic or local irritation, gastrointestinal disorders (such as nausea, vomiting, indigestion, diarrhea, dysphagia), anorexia, dizziness, headache, fatigue, sleep disorders, abnormal mental status, sexual dysfunction, abnormal vision, dyspnea etc.. Fluoxetine should be banned for those who are using drugs such as monoamine oxidase inhibitor (MAOI). For hepatic insufficiency, the half-life of fluoxetine and norfluoxetine is increased to 7 days and 14 days respectively. Therefore, it is important to consider reducing the dosage or reducing the frequency of drug use.
Uses	antibacterial
Uses	Rivastigmine Metabolite

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;

Recommended supplier

Product name	Price		Suppliers	Update time
Fluoxetine	$50.00/1kg	VIP4Y	Hebei Yanxi Chemical Co., Ltd.	2023-09-13
Fluoxetine	$0.00/100g		Wuhan Han Sheng New Material Technology Co.，Ltd	2023-07-17
Fluoxetine	$0.00/10mg	VIP1Y	Hangzhou ICH Biofarm Co., Ltd	2023-07-07
Fluoxetine	$350.00/1KG	VIP4Y	Hebei Lingding Biotechnology Co., Ltd.	2023-07-05
Fluoxetine	$50.00/1KG		Wuhan Boyuan Import & Export Co., LTD	2023-04-10
Fluoxetine	$10.00/1000kg		Shijiazhuang Suking Biotechnology Co .,Ltd.	2023-03-14
Fluoxetine	$30.00/1KG		Weijer International Trade (Hebei) Co., Ltd	2023-03-09
Fluoxetine	$0.00/1kg		henan kanbei chemical co.,ltd	2022-09-22
Fluoxetine	$0.00/1kg	VIP2Y	Henan Aochuang Chemical Co.,Ltd.	2022-09-22
Fluoxetine	$10.00/1KG		Shanxi Naipu Import and Export Co.,Ltd	2021-09-17

Product Details

Company Profile Introduction

You may like

Recommended supplier

career henan chemical co