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Postion:Product Catalog >API>Circulatory system drugs>Antiarrhythmics Drugs>Sotalol hydrochloride
Sotalol hydrochloride
  • Sotalol hydrochloride

Sotalol hydrochloride

Price $1
Package 1kg
Min. Order: 1g
Supply Ability: 100KG
Update Time: 2019-07-06

Product Details

Product Name: Sotalol hydrochloride CAS No.: 959-24-0
Min. Order: 1g Purity: 99%
Supply Ability: 100KG Release date: 2019/07/06
Product:: AD68
Sotalol hydrochloride Basic information
Product Name: Sotalol hydrochloride
Synonyms: 4-(2-isopropylamino-1-hydroxyaethyl)methanesulfonailidhydrochlorid;4’-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilidemonohydrochloride;4’-(1-hydroxy-2-(isopropylamino)ethyl)-methanesulfonanilidmonohydrochlorid;isopropylaminohydroxyethylmethanesulfonanilidehydrochloride;meadjohnson1999;n-isopropyl-beta-(4-methanesulfonamidophenyl)ethanolaminehydrochloride;4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilide hydrochloride;BETAPACE
CAS: 959-24-0
MF: C12H21ClN2O3S
MW: 308.82
EINECS: 213-496-0
Product Categories: Miscellaneous Natural Products;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Adrenoceptor;Amines;Aromatics;Sulfur & Selenium Compounds;EXCENEL
Mol File: 959-24-0.mol
Article illustration
 
Sotalol hydrochloride Chemical Properties
Melting point  218-220°C
storage temp.  Store at RT
solubility  H2O: 20 mg/mL
form  powder
color  white to off-white
Water Solubility  Soluble in phosphate buffered saline, DMSO, ethanol, water, and methanol.
CAS DataBase Reference 959-24-0(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  PB0826000
Toxicity LD50 in male mice, rats (mg/kg): 2600, 3450 orally; 670, 680 i.p.; LD50 orally in rabbits: 1000 mg/kg; LD50 i.p. in dogs: 330 mg/kg (Lish)
MSDS Information
Provider Language
SigmaAldrich English
 
Sotalol hydrochloride Usage And Synthesis
Chemical Properties White Crystalline Solid
Uses A potent -adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period
Uses A potent α-adrenergic receptor antagonist. A class III antiarrythmic. It has been shown to prolong action potential and increases the refractory period.
Uses antibacterial
Definition ChEBI: A hydrochloride salt that is the monohydrochloride of sotalol. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Brand name Betapace(Berlex); Sorine (Upsher Smith).
Biological Activity A relatively potent pure β adrenergic antagonist, unique in possessing additional class III antiarrhythmic activity. Also available as part of the Mixed Adrenergic Tocriset™ .

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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