Antiarrhythmics Drugs

Anti-arrhythmic drugs generally refer to the drugs for the prevention and treatment of tachycardia arrhythmia. In recent years, due to the in-depth study of electrophysiology, people have a further understanding of the mechanism of antiarrhythmic drugs; the establishment of micro-assay of drug content in the body enables the medicine treatment designing to control arrhythmia according to the pharmacokinetic principles; with the continuous monitoring on the electrocardiogram and the help of computer, we can obtain the relationship between the plasma concentration of patients and the clinical efficacy of drugs. All of these advances have contributed to the discovery of new drugs and the treatment of arrhythmias. According to the electrophysiological characteristics of antiarrhythmic drugs, several classification methods of Anti-arrhythmic drugs have been proposed. They are usually divided into the following four categories-membrane-stabilizing agents, action potential duration and refractory period extenders, beta-blockers and calcium antagonists. But the first two are also known as non-specific anti-arrhythmic drugs and the latter two as specific anti-arrhythmic drugs.
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Structure Chemical Name CAS MF
Dronedarone Dronedarone 141626-36-0 C31H44N2O5S
Dofetilide Dofetilide 115256-11-6 C19H27N3O5S2
Quinidine Quinidine 56-54-2 C20H24N2O2
Atenolol Atenolol 29122-68-7 C14H22N2O3
QUINIDINE SULFATE QUINIDINE SULFATE 50-54-4 C40H50N4O8S
Propranolol hydrochloride Propranolol hydrochloride 318-98-9 C16H22ClNO2
Mexiletine hydrochloride Mexiletine hydrochloride 5370-01-4 C11H18ClNO
Bisoprolol fumarate Bisoprolol fumarate 104344-23-2 C22H35NO8
Amiodarone hydrochloride Amiodarone hydrochloride 19774-82-4 C25H29I2NO3.ClH
Procainamide hydrochloride Procainamide hydrochloride 614-39-1 C13H22ClN3O
Metoprolol tartrate Metoprolol tartrate 56392-17-7 2C15H25NO3.C4H6O6
(+/-)-Verapamil hydrochloride (+/-)-Verapamil hydrochloride 152-11-4 C27H39ClN2O4
(-)-SPARTEINE (-)-SPARTEINE 90-39-1 C15H26N2
Antazoline hydrochloride Antazoline hydrochloride 2508-72-7 C17H20ClN3
5-(4-Methylphenyl)-1H-tetrazole 5-(4-Methylphenyl)-1H-tetrazole 24994-04-5 C8H8N4
Cibenzoline Cibenzoline 53267-01-9 C18H18N2
AZIMILIDE AZIMILIDE 149908-53-2 C23H28ClN5O3
IBUTILIDE IBUTILIDE 122647-31-8 C20H36N2O3S
PACHYCARPINE PACHYCARPINE 492-08-0 C15H26N2
5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one 5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one 51781-06-7 C16H24N2O3
Flecainide Flecainide 54143-55-4 C17H20F6N2O3
D-Timolol maleate D-Timolol maleate 26839-77-0 C17H28N4O7S
1-Isopropylamino-3-(naphthalen-1-yloxy)-propan-2-ol 1-Isopropylamino-3-(naphthalen-1-yloxy)-propan-2-ol 525-66-6 C16H21NO2
Betaxolol Betaxolol 63659-18-7 C18H29NO3
Metoprolol Metoprolol 51384-51-1 C15H25NO3
DISOPYRAMIDE DISOPYRAMIDE 3737-09-5 C21H29N3O
1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one hydrochloride 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one hydrochloride 34183-22-7 C21H28ClNO3
Propafenone Propafenone 54063-53-5 C21H27NO3
SPARTEINE SULFATE SPARTEINE SULFATE 299-39-8 C15H28N2O4S
Quinidine sulfate dihydrate Quinidine sulfate dihydrate 6591-63-5 2C20H24N2O2.2H2O.H2O4S
NADOLOL NADOLOL 42200-33-9 C17H27NO4
PILSICAINIDE PILSICAINIDE 88069-67-4 C17H24N2O
Pindolol Pindolol 13523-86-9 C14H20N2O2
Betaxolol hydrochloride Betaxolol hydrochloride 63659-19-8 C18H30ClNO3
OXPRENOLOL HYDROCHLORIDE OXPRENOLOL HYDROCHLORIDE 6452-73-9 C15H24ClNO3
Metoprolol Metoprolol 37350-58-6 C15H25NO3
LEVOBUNOLOL LEVOBUNOLOL 47141-42-4 C17H25NO3
BRETYLIUM TOSYLATE BRETYLIUM TOSYLATE 61-75-6 C18H24BrNO3S
Amiodarone Amiodarone 1951-25-3 C25H29I2NO3
Verapamil Verapamil 52-53-9 C27H38N2O4
Acebutolol Acebutolol 37517-30-9 C18H28N2O4
Indeloxazine hydrochloride Indeloxazine hydrochloride 65043-22-3 C14H18ClNO2
HYDROQUINIDINE HYDROQUINIDINE 1435-55-8 C20H26N2O2
Bisoprolol Bisoprolol 66722-44-9 C18H31NO4
Antazoline Antazoline 91-75-8 C17H19N3
Lorcainide Lorcainide 59729-31-6 C22H27ClN2O
Indeloxazine Indeloxazine 60929-23-9 C14H17NO2
FLECAINIDE ACETATE FLECAINIDE ACETATE 54143-56-5 C19H24F6N2O5
Esmolol hydrochloride Esmolol hydrochloride 81161-17-3 C16H26ClNO4
1-(2,6-Dimethylphenoxy)-2-propanamine 1-(2,6-Dimethylphenoxy)-2-propanamine 31828-71-4 C11H17NO
Pilsicainide hydrochloride Pilsicainide hydrochloride 88069-49-2 C17H24N2O
Sotalol hydrochloride Sotalol hydrochloride 959-24-0 C12H21ClN2O3S
AROTINOLOL HCL AROTINOLOL HCL 68377-91-3 C15H22ClN3O2S3
Celiprolol hydrochloride Celiprolol hydrochloride 57470-78-7 C20H34ClN3O4
Befunolol Befunolol 39552-01-7 C16H21NO4
Aprindine Aprindine
Encainide Encainide 37612-13-8 C22H28N2O2
Isosparteine Isosparteine 24915-04-6
(S)-(-)-METOPROLOL (S)-(-)-METOPROLOL 81024-42-2 C15H25NO3
R(+)-PROPRANOLOL HCL R(+)-PROPRANOLOL HCL 5051-22-9 C16H22ClNO2
Demethyl-Coclaurine Demethyl-Coclaurine 5843-65-2 C16H17NO3
Pyrozoline Pyrozoline
Timolol Timolol 26839-75-8 C13H24N4O3S
ESMOLOL ESMOLOL 103598-03-4 C16H25NO4
oxprenolol oxprenolol 6452-71-7 C15H23NO3
N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride   N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride 58934-46-6 C22H28Cl2N2O
N-[4-[2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETAMIDE N-[4-[2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY]PHENYL]ACETAMIDE 6673-35-4 C14H22N2O3
AROTINOLOL AROTINOLOL 68377-92-4 C15H21N3O2S3
Levobunolol hydrochloride Levobunolol hydrochloride 27912-14-7 C17H26ClNO3
procainamide  procainamide 51-06-9 C13H21N3O
AJMALINE AJMALINE 4360-12-7 C20H26N2O2
Sotalol Sotalol 3930-20-9 C12H20N2O3S
Carteolol hydrochloride Carteolol hydrochloride 51781-21-6 C16H25ClN2O3
QUINIDINE GLUCONATE QUINIDINE GLUCONATE 7054-25-3 C26H36N2O9
Esmolol Esmolol 81147-92-4 C16H25NO4
Disopyramid phosphate Disopyramid phosphate 22059-60-5 C21H32N3O5P
Alprenolol Alprenolol 13655-52-2 C15H23NO2
PROPRANOLOL HYDROCHLORIDE PROPRANOLOL HYDROCHLORIDE 3506-09-0 C16H22ClNO2
TOCAINIDE TOCAINIDE 41708-72-9 C11H16N2O
Celiprolol Celiprolol 56980-93-9 C20H33N3O4
N-ACETYLPROCAINAMIDE N-ACETYLPROCAINAMIDE 32795-44-1 C15H23N3O2
(R)-(+)-METOPROLOL (R)-(+)-METOPROLOL 81024-43-3 C15H25NO3
Tocainide hydrochloride Tocainide hydrochloride 35891-93-1 C11H17ClN2O
Butofilolol Butofilolol
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