Product Details
| Product Name:
KU-55933 |
CAS No.:
587871-26-9 |
| Min. Order:
1kg |
Purity:
99% |
| Supply Ability:
100kg |
Release date:
2019/07/06 |
| ProductNumber::
WM.697 |
| KU-55933 Basic information |
| Product Name: |
KU-55933 |
| Synonyms: |
2-MORPHOLIN-4-YL-6-THIANTHREN-1-YL-PYRAN-4-ONE;2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one;KU-55933 (ATM Kinase Inhibitor);KU-55933, >99%;KV-55933;2-morpholino-6-(thianthren-1-yl)-4H-pyran-4-one;2-Morpholin-4-yl-6-thianthren-1-ylpyran-4-one KU-55933 (ATM Kinase Inhibitor);KU 55933, >=98% |
| CAS: |
587871-26-9 |
| MF: |
C21H17NO3S2 |
| MW: |
395.49 |
| EINECS: |
|
| Product Categories: |
Inhibitors |
| Mol File: |
587871-26-9.mol |
 |
| |
| KU-55933 Chemical Properties |
| storage temp. |
Desiccate at -20°C |
| |
| KU-55933 Usage And Synthesis |
| Uses |
A potent and specific ATM kinase inhibitor with an IC50 and a Ki of 13 nM and 2.2 nM, respectively. |
| Biological Activity |
Potent, selective and competitive ATM kinase inhibitor (K i = 2.2 nM, IC 50 values are 13, 2500, 9300, 16600, > 100000 and > 100000 nM at ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively). Decreases viability of MCF-7, A549 and HCT116 cells and decreases p21 CIP1 levels in vitro . Acts as a radio- and chemosensitizer for the treatment of cancer. |
| |
| KU-55933 Preparation Products And Raw materials |
Tag:
KU-55933(587871-26-9) Related Product InformationNU7441 (KU-57788) Bortezomib Y27632 (hydrochloride) VE-821 KU-60019 Olaparib KU-55933 (ATM Kinase Inhibitor) Thianthrene
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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