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Postion:Product Catalog >API>Antineoplastic agents>Hormonal antineoplastic drugs>Tamoxifen
Tamoxifen
  • Tamoxifen

Tamoxifen

Price Get Latest Price
Package 25Kg/Drum
Min. Order: 1KG
Supply Ability: 20tons
Update Time: 2019-07-22

Product Details

Product Name: Tamoxifen CAS No.: 10540-29-1
EC-No.: 234-118-0 Min. Order: 1KG
Purity: 99% Supply Ability: 20tons
Release date: 2019/07/22
MF:: C26H29NO Skype/Email:: sales@luchibiology.com

99% Purity Anti Estrogen Steroid Powder Tamoxifens

Basic info:

Name:  Tamoxifens
Other name: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxyl]-N,N-dimethyl-ethanamine-citrate; 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate  
Appearance: white crystalline powder
EINECS:259-415-2
MF:C32H37NO8
MW:563.64
Assay:99%min
Place of Origin:China
Certification:ISO9001
Package: 25KG/Drum   5kg/tin
MP: 140-144 ºC
Loss on drying:≤0.5%, 
Usage:  Applied to the treatment of advanced, recurrent breast cancer and ovarian cancer.

COA:

Product name T`amoxifen citrate (N`olvadex)
Appearance White crystalline powder
Identification IR , UV conform Conform
Loss on drying ≤0.5ml 0.21ml
Residue on ignition Not more than 0.2% 0.07ml
Iron Not more than 0.005% 0.0017%
Heavy metals Not more than 0.001% 0.0006%
Related substances Total: Not more than 1.0%
Individual: Not more than 0.5%
0.35%
0.13%
E-isomer Not more than 0.3% 0.18%
Organic volatile impurities Conforms Conforms
Assay 99.0~101.0% 99.6%

 


What is Tamoxifens:
         Tamoxifens is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure. It is not correct that Tamoxifens reduces levels of estrogen: Rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.
       The claim that Tamoxifens reduces gains should not be taken too seriously. The fact is that any number of bodybuilders have made excellent gains while using Tamoxifens.
The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction  (individuals using anabolic steroids were not studied though) from use of Tamoxifens.
 
What is it application: 
      is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifens. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. is the usual endocrine (anti-estrogen) therapy forhormonereceptor-positivebreast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting. 
    is metabolized into compounds that also bind to the estrogen receptor but do not activate it. Because of this competitive antagonism, acts like a key broken off in the lock that prevents any other key from being inserted, preventing estrogen from binding to its receptor. Hence breast cancer cell growth is blocked.
 
The note of Tamoxifens:
    1. Before using this medicine, tell your doctor about any disease, especially prostate cancer or breast cancer (male), liver, heart, kidney disease, allergies, and enlarged prostate cancer. High - dose, long - term use of male hormones, liver cancer;
    2. This medicine can not be used during pregnancy. If you are pregnant or think you may be pregnant, immediately notify your doctor. Breastfeeding at the same time, should avoid using this drug;
    3. Women should monitor masculine signs such as deepening of sound, beard, acne, irregular menstruation, or clitoral enlargement. If any of these occurs, consult your doctor in a timely manner;
   4. Children should be very cautious, because the drug may have adverse effects on child development. Older men use this drug, there is prostate enlargement or prostate cancer risk.

Company Profile Introduction

Handan Zhengle Biological Technology Co., Ltd .who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. Our company is honored as the high-tech enterprise which engaged in researching, developing, manufacturing and exporting research chemicals,advanced pharmaceutical intermediates and Active Pharmaceutical Ingredients (API), include kinds of research chemicals, We have own labs to do research,we provide many kinds of research chemicals. We have established a broad customer base in America, Australia,Russia and other European countries, We have built many long business relationship with our customers. We base our goods with all our power so it will definitely meet and surpass every buyer's highest expectations. We guarantee that after purchasing from us , you will never look anywhere else again!

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  • Since: 2017-03-29
  • Address: Traffic Lane,Congtai District, Handan City,Hebei, China
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