Gamma cyclodextrin

[Pharmaceutical grade gamma cyclodextrin] features:
l Can provide synthetic routes, testing methods, production processes and other related documents.
l The γ-cyclodextrin cavity can cover a wider range of guest molecules, and should have a larger cavity than gamma cyclodextrin and β-cyclodextrin and alpha cyclodextrin;
l Gamma cyclodextrin has better water solubility in water, the solubility of γ-cyclodextrin is 25.6g/100ml at room temperature 25°C, and the solubility of α-cyclodextrin is 12.7g/100ml water, b-cyclodextrin The solubility is only 1.88 g / 100 ml of water.
l Gammacyclodextrin has higher solubility in various polar organic solvents than beta-cyclodextrin.
 
[Pharmaceutical grade gamma cyclodextrin] basic information:
 
Product name : Pharmaceutical grade gamma cyclodextrin
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CAS NO. : 17465-86-0
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Alias: γ-cyclodextrin; gamma cyclodextrin;
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Abbreviation : GCD
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Quality : Pharmaceutical grade
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Molecular formula : C48H80O40
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Molecular weight : 1297.12
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[Pharmaceutical grade gamma cyclodextrin] main use:
Gamma cyclodextrin (gamma-cyclodextrin) is a non-reducing cyclic saccharide that is an odorless, white or nearly white crystalline solid. It is formed by cyclizing 8 glucose units via D-glucopyranose units linked by α-1,4-linkage.
 
The use of gamma cyclodextrin in the pharmaceutical industry utilizes cyclodextrin to form inclusions (encapsulation) with drugs, which can stabilize unstable drugs; deliquescent, adhesive or liquid drug powdering; poorly soluble Or insoluble drugs can be solubilized (solubilized) and the like.
 
[Pharmaceutical grade gamma cyclodextrin] quality standard

       Gamma cyclodextrin quality standard
 
       CAS No.: 17465-86-0
 
  Inspection basis
  Inspection item
  Character is white powder
  Identification The retention time of the main peak of the test solution and the reference solution is the same;
  Optical rotation +174°～ +180°
  Solution clarity, clear and colorless
  Content 98.0% ~ 102.0%
  Reducing sugar ≤0.2%
  Water content ≤11.0%
  Residue on ignition ≤0.1%
  Heavy metal ≤5.0ppm
 
  Microbial aerobic bacteria total ≤1000cfu/g
  Mold, yeast ≤100cfu/g
  Escherichia coli cannot be detected
[Pharmaceutical grade gamma cyclodextrin] packaging:
1kg/1 aluminum foil bag, 25kg/1 barrel