HISPIDULIN

Product Name: HISPIDULIN

Synonyms: Hispidulin, >99%;SCUTELLAREIN 6-METHYL ETHER;4',5,7-Trihydroxy-6-methoxyflavone;5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one;6-Methoxyapigenin;6-Methylscutellarein;Hispidulin(Dinatin);Methoxyapigenin

CAS: 1447-88-7

MF: C16H12O6

MW: 300.26

EINECS:

Product Categories: Miscellaneous Natural Products

Mol File: 1447-88-7.mol

HISPIDULIN Structure

HISPIDULIN Chemical Properties

Melting point 291-292 °C

Boiling point 601.5±55.0 °C(Predicted)

density 1.512±0.06 g/cm3(Predicted)

storage temp. Desiccate at -20°C

solubility DMSO: soluble20mg/mL, clear

pka 6.51±0.40(Predicted)

form powder

color white to beige

Safety Information

Hazard Codes Xn

Risk Statements 22

WGK Germany 3

RTECS DJ2996000

MSDS Information

HISPIDULIN Usage And Synthesis

Definition ChEBI: A monomethoxyflavone that is scutellarein methylated at position 6.

Biological Activity Partial positive allosteric modulator at the benzodiazepine receptor (IC 50 = 1.3 μ M for inhibition of flumazenil binding); natural sage flavone. Stimulates GABA-induced chloride currents in Xenopus oocytes expressing α 1 α 2-, α 3-, α 5- or α 6- β 2 γ 2S GABA A receptors. Brain penetrant; oral administration reduces seizures in a gerbil model of epilepsy. Also has antifungal, antiproliferative, antioxidant and antithrombotic properties.