Afoxolaner NEW
| Price | $36 | $61 | $117 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-03 |
Product Details
| Product Name: Afoxolaner | CAS No.: 1093861-60-9 |
| Purity: 99.93% | Supply Ability: 10g |
| Release date: 2025/12/03 |
Product Introduction
Bioactivity
| Name | Afoxolaner |
| Description | Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod. |
| In vivo | A single oral administration of afoxolaner at a dose near the minimum effective (2.5mg/kg) eradicated existing I. scapularis tick infestations and managed weekly re-infestations effectively. Efficiencies ranged from 98% to 100% up to Day 23 and remained at 94% on Day 30 [1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : ≥ 250 mg/mL (399.44 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.2 mM), Sonication is recommended. |
| Keywords | γ-Aminobutyric acid Receptor | scapularis | Parasite | Ixodes | isoxazoline | insecticide | insect | Inhibitor | inhibit | Gamma-aminobutyric acid Receptor | GABAReceptor | GABA Receptor | GABA | dog | Cl? Channels | Chloridechannel | Chloride Channel | Chloride channel | arthropod | Afoxolaner | acaricide |
| Inhibitors Related | Flubendazole | Kojic acid | p-Hydroxybenzaldehyde | Urethane | Hydroxychloroquine | Metronidazole | 2-Amino-2-methyl-1-propanol | Doxycycline | Valproic Acid | Fenpyroximate | Methylene Blue trihydrate | Coumaran |
| Related Compound Libraries | Anti-Parasitic Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Membrane Protein-targeted Compound Library | Anti-Parkinson's Disease Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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