Baicalein NEW

Nutural Plant Extract  Baicalein CAS:491-67-8

Product Name:Baicalein

Synonyms:BAICALEIN(SH)NOW RG GRADE;Baicalein, monohydrate, 5,6,7-Trihydroxy-2-phenyl-4H-chromen-4-one monohydrate;Baicelein;Noroxylin;5,6,7-trihydroxy-2-phenyl-4H-chroMen-4-one;Baicalein 98%;5,6,7-trihydroxy-2-phenyl-4-chromenone hydrate;Baicaleine

CAS:491-67-8

MF:C15H10O5

MW:270.24

Melting point:256-271 °C (lit.)

Boiling point:373.35°C (rough estimate)

density:1.3280 (rough estimate)

refractive index:1.5000 (estimate)

storage temp.:Keep in dark place,Sealed in dry,2-8°C

solubility:DMSO (Slightly), Methanol (Slightly)

pka:6.31±0.40(Predicted)

form:Yellow solid

color:Yellow or yellow-green

Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.

Chemical Properties:Yellow Crystalline Solid

Description   

Baicalein (491-67-8) is an inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis.1?Originally reported as a selective inhibitor of 12-lipoxygenase, baicalein has since been shown to inhibit both 12-LO and 15-LO (IC50=0.64 μM for 12-LO and 1.6 μM for 15-LO).2 Baicalein displays anti-inflammatory activity and inhibits adjuvant-induced arthritis. Also inhibits prolyl oligopeptidase (IC50=36 μM).3