Dextran sulfate sodium salt (MW 5000) NEW
| Price | $40 |
| Package | 10g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-12-04 |
Product Details
| Product Name: Dextran sulfate sodium salt (MW 5000) | CAS No.: 9011-18-1 |
| Supply Ability: 10g | Release date: 2025/12/04 |
Product Introduction
Bioactivity
| Name | Dextran sulfate sodium salt (MW 5000) |
| Description | Dextran sulfate sodium salt (MW 4500-5500) is a polymer of dehydrated glucose and an inhibitor of complement and coagulation pathways. Dextran sulfate sodium salt (MW 4500-5500) can be used as an anticoagulant, antiviral agent and antilipidemic agent. Dextran sulfate sodium salt (MW 4500-5500) can prevent the HIV-1 virus from adsorbing onto host cells. Dextran sulfate sodium salt (MW 4500-5500) can inhibit NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 4500-5500) can inhibit the immediate blood-mediated inflammatory response (IBMIR). |
| In vitro | METHODS: MT-4 cells were treated with Dextran sulfate sodium salt (MW 4500-5500) (25 μg/mL) for 24 hours. The inhibitory effect on HIV-1 replication was observed, and the effects of the drug on cytotoxicity and reverse transcriptase activity were evaluated. RESULTS: Dextran sulfate sodium salt (MW 4500-5500) has a significant selective inhibitory effect on HIV-1, with an IC50 value of 2.3-8.8 µg/ml, and does not show toxicity to host cells at high concentrations. [1] |
| In vivo | METHODS: To investigate the effect of Dextran sulfate sodium salt (MW 4500-5500) on endothelial injury after ischemia and reperfusion in a rat model of inferior renal aortic clamp, Dextran sulfate sodium salt (MW 4500-5500)(5 mg/mL, 200 μL) was immediately locally infused into the ischemic aortic segment of rats before reperfusion. RESULTS: Dextran sulfate sodium salt (MW 4500-5500) inhibits complement activation and reduces endothelial injury after ischemia and reperfusion in the rat model of inferior renal aortic clamp. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 100 mg/mL, Sonication is recommended. DMSO : Insoluble |
| Keywords | HIVProtease | HIV Protease | HIV | Dextran sulfate sodium | Apoptosis |
| Inhibitors Related | Stavudine | Aceglutamide | Emtricitabine | Cysteamine hydrochloride | Urea | Sodium 4-phenylbutyrate | Lamivudine | Metronidazole | Citric Acid Triammonium | Tributyrin | L-Methionine | Alginic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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