DOTAP chloride NEW
| Price | $31 | $44 | $81 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-05 |
Product Details
| Product Name: DOTAP chloride | CAS No.: 132172-61-3 |
| Purity: 99.97% | Supply Ability: 10g |
| Release date: 2025/11/05 |
Product Introduction
Bioactivity
| Name | DOTAP chloride |
| Description | DOTAP chloride (1, 2-dioleoyl-3-trimethylammonium-propane chloride) is an efficient cationic lipid, and its target is mainly the negatively charged components on the cell membrane. DOTAP chloride binds to negatively charged nucleic acids (such as DNA and RNA) by electrostatic interaction to form complexes, thereby achieving the delivery of nucleic acids. |
| In vitro | METHODS: Prostate cancer cell line PC3 and melanoma cell line M21 were treated with paclitaxel (PTX) loaded on DOTAP/DOPC liposome carriers (CLs) for 24 hours. The cytotoxicity was detected by measuring the absorbance at 490 nm using an enzyme-linked immunosorbent assay reader. RESULTS: With the increase of PTX content, the cytotoxic effect of DOTAP/DOPC CLs is enhanced. [1] |
| Storage | store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | Ethanol : 130 mg/mL (186.1 mM), Sonication and heating are recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (5.73 mM), Sonication is recommended. DMSO : 125 mg/mL (178.94 mM), Sonication is recommended. |
| Keywords | transfection | nucleic | Lipid | Inhibitor | inhibit | DOTAP chloride | DOTAP Chloride | DOTAP | Cationic Lipid | Cationic | acid | 1,2-Dioleoyl-3-trimethylammonium-propane Chloride |
| Inhibitors Related | 1,2-Distearoyl-sn-glycero-3-phosphorylcholine | SM-102 | 1,2-dioleoyl-sn-glycero-3-phosphocholine | DODAP | DPPC | D-Lin-MC3-DMA | 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC | ALC-0315 | DSPS | Cholesterol | Phosphatidylcholines,soya | 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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