Exemestane

‌Exemestane | CAS 107868-30-4‌
🌟 ‌Product Overview‌
Exemestane, a steroidal aromatase inhibitor with molecular formula ‌C₂₀H₂₄O₂‌ and molecular weight ‌296.4 g/mol‌, is primarily used in the treatment of ‌hormone receptor-positive breast cancer‌ in postmenopausal women‌14. It works by irreversibly inhibiting the aromatase enzyme, thereby reducing estrogen synthesis and slowing tumor growth‌45. Widely applied in pharmaceuticals and research, it is essential for oncology and endocrine disorder studies‌12.

💡 ‌Key Advantages‌
✅ ‌High Purity & Stability‌
≥98% purity (USP standards) with ‌24-month stability‌ under ‌room temperature, dry, and light-protected storage‌‌12.

🔬 ‌Targeted Efficacy‌
Demonstrates potent aromatase inhibition (IC₅₀ = ‌27 nM‌), validated in preclinical and clinical studies for breast cancer therapy‌45.

🛡️ ‌Regulatory Compliance‌
Manufactured under ‌GMP‌ guidelines and compliant with ‌USP‌ analytical standards, ensuring pharmaceutical-grade quality‌24.

📊 ‌Applications‌

• ‌Pharmaceuticals‌: Core component in ‌aromatase inhibitor therapies‌ for advanced or metastatic breast cancer‌

• ‌Research‌: Used in steroid metabolism studies, anti-aging research, and molecular biology experiments‌

• ‌Biochemical Synthesis‌: Intermediate in steroid hormone production and enzyme inhibition assays‌

🔍 ‌Quality Certifications‌

• Complies with ‌USP‌ and ‌EP‌ pharmacopeia standards‌.

• Batch-specific ‌COA (Certificate of Analysis)‌ and stability reports provided‌.

📈 ‌Market Trends‌
The global breast cancer therapeutics market is projected to grow at a ‌CAGR of 7.3% (2025-2030)‌, driven by rising oncology R&D and demand for targeted hormone therapies‌5. Exemestane remains a critical agent in personalized cancer treatment regimens.