Flupirtine Maleate NEW

Factory Provide Analgesic CAS 75507-68-5 Flupirtine Raw Material Flupirtine Maleate Powder

Introduction

Product Name :Flupirtine Maleate

Othe name :2-AMINO-6-[[(4-FLUOROPHENYL)METHYL]AMINO]-3-PYRIDINYL]-CARBAMIC ACID, ETHYL ESTER MALEATE;Flupirtinemaleatelupirtine

CAS No. 75507-68-5

EINECS No. 278-225-0

Molecular Formula: C19H21FN4O6

MW:420.3916432

Assay: 99%
Appearance: White powder
Melting Point :186-188°C

Storage :Keep in a cool, dry, dark location

  Flupirtine maleate is a selective neurogenic potassium channel opener. It is easily absorbed by oral administration. It has three functions of pain relief, muscle relaxation and neuroprotection. It has analgesic effect on pain caused by various reasons. It has no affinity with opioid receptors, nor does it inhibit the synthesis of Chemicalbook prostaglandins. It is not antagonized by naloxone. Its analgesic strength (ED50) is weaker than that of methadona, buprenorphine and morphina, which is about 50% of that of morphina. Zocine is equivalent, stronger than pethidina, codeina, phenaceti and acetaminophen.

Application
Flupirtine maleate has an inhibitory effect on pain caused by various diseases, and its analgesic effect is between methadona and paracetamol. It acts on the center, but does not inhibit the respiratory and cardiovascular systems and affect the pharmacological activity of the cough center, nor does it produce constipation and urinary retention. Long-term use does not produce tolerance and dependence. No side effects of painkillers on the market, such as addiction, digestive tract symptoms, etc. After long-term use for several years, the curative effect will not be reduced, but the dosage can be reduced. In short, flupirtine maleate has good clinical application prospects.