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Postion:Product Catalog >API>Digestive system drugs>Laxatives and Antidiarrheal Medicines>Loperamide hydrochloride
Loperamide hydrochloride
  • Loperamide hydrochloride
  • Loperamide hydrochloride
  • Loperamide hydrochloride
  • Loperamide hydrochloride
  • Loperamide hydrochloride

Loperamide hydrochloride NEW

Price Get Latest Price
Package 1KG 5KG 25KG
Min. Order: 1KG
Supply Ability: 20 T each week
Update Time: 2023-08-11

Product Details

Product Name: Loperamide hydrochloride CAS No.: 34552-83-5
EC-No.: 252-082-4 Min. Order: 1KG
Purity: 98%~99% Supply Ability: 20 T each week
Release date: 2023/08/11

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Contact : we chat/whatsapp ID: +8613176845580 ross@zhongda-biotech.com

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Product Name:Loperamide hydrochloride
Synonyms:4-(4-(p-chlorophenyl)-4-hydroxy-1-piperidyl)-n,n-dimethyl-2,2-diphenylbutyra;4-(p-chlorophenyl)-4-hydroxy-n,n-dimethyl-alpha,alpha-diphenyl-1-piperidine;blox;butyramidehcl;dissenten;fortasec;imodium;imosec
CAS:34552-83-5
MF:C29H34Cl2N2O2
MW:513.5
EINECS:252-082-4
Product Categories:IMODIUM;Other APIs;ACTIVE PHARMACEUTICAL INGREDIENTS;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Opioid receptor and opioid-like receptor;Amines;Heterocycles;34552-83-5
Mol File:34552-83-5.mol
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Loperamide hydrochloride Chemical Properties
Melting point 223-225°C
density 1.1905 (rough estimate)
refractive index 1.6100 (estimate)
storage temp. 2-8°C
solubility Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol.
form neat
pka8.66(at 25℃)
color White to Almost white
Merck 14,5571
CAS DataBase Reference34552-83-5(CAS DataBase Reference)

Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS TM4960000
HazardClass 6.1(b)
PackingGroup III
HS Code 29333990
ToxicityLD50 in mice (mg/kg): 75 s.c.; 28 i.p.; 105 orally; in rats (mg/kg): 185 orally (Niemegeers)
MSDS Information
ProviderLanguage
SigmaAldrichEnglish

Loperamide hydrochloride Usage And Synthesis
Chemical PropertiesWhite Solid
OriginatorImodium,Janssen,UK,1975
UsesLabeled Loperamide, which is used as an antidiarrheal
UsesCa channel blocker
UsesLoperamide hydrochloride is a Ca2+ channel protein inhibitor and MOR activator.
IndicationsLoperamide hydrochloride (Imodium) structurally resembles both haloperidol and meperidine. In equal doses, loperamide protects against diarrhea longer than does diphenoxylate. It reduces the daily fecal volume and decreases intestinal fluid and electrolyte loss. Loperamide produces rapid and sustained inhibition of the peristaltic reflex through depression of longitudinal and circular muscle activity.The drug also possesses antisecretory activity, presumably through an effect on intestinal opioid receptors.
DefinitionChEBI: A hydrochloride obtained by combining loperamide with one equivalent of hydrochloric acid. Used for treatment of diarrhoea resulting from gastroenteritis or inflammatory bowel disease.


Company Profile Introduction

Shandong Huisheng Import & Export Co., Ltd. is located in Jinan city, Shandong Province, is a collection of domestic trade, international trade in one of the diversified services company. Our goal is to provide customers with high quality solutions and one-stop purchasing experience. At present, the company business scope involves five areas: Organic chemical raw materials, inorganic chemical raw materials, fine chemical raw materials, dangerous chemicals and green environmental protection chemical technology project promotion, and we has also established good relations of cooperation with several well-known enterprises and won the strong support of extensive trust from the new and old customers. Products are widely used in automobile, household appliances, office supplies, mobile phone accessories, routers, food, medical and other fields. At present, our business covers 30 countries, and our customers mainly come from Australia, New Zealand, Canada, Germany, France, Poland, South Korea, Russia, Bangladesh, Vietnam, Kazakhstan, India, Ghana, Nigeria, South Africa, Egypt and other more than 30 countries. The company has a sound quality management system and advanced professional equipment, with a positive attitude to meet the changing needs of customers. We take "quality products, quality service, competitive price, timely delivery" as the purpose, looking forward to greater cooperation with overseas customers on the basis of mutual benefit. Our company provides a wide range of products to meet your various needs. Since its inception, the company has always adhered to the "quality first, customer first, reputation first" business policy, wholeheartedly meet the potential needs of our customers. Under the irresistible situation of economic globalization, our company is willing to cooperate sincerely with enterprises around the world to achieve a win-win situation.

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