Nystatin

Product category: pharmaceutical raw materials and intermediates

Product content: 99%

Chemical formula: C47H75NO17 nystatin

CAS No.: 1400-61-9

Quality standard: USP26

Drug alias: Mycostatin, Fungicidine

Preparation specification: tablets: 100000 U, 250000 U, 500000 U.

Product description: Nystatin is a yellow or yellow-brown powder with special odor and hygroscopic bacteria spectrum and mechanism similar to amphotericin B. It is mainly used for skin, mucous membrane, oral cavity

Pharmacology and toxicology: Polyene drugs have broad-spectrum effects and high activity against Candida. Cryptococcus neoformans, Aspergillus, Mucor, Microsporium, Histoplasma capsulatum, Blastomyces and dermatophytes are usually sensitive to this product.

Nystatin can combine with sterols on the fungal cell membrane to change the permeability of the cell membrane, so that important cell contents are lost and play a role.

Pharmacokinetics: Nystatin is not absorbed in the gastrointestinal tract after oral administration, and the blood drug concentration is extremely low after oral administration, which has no effect on the whole body. Almost all the dosage is discharged from the stool. Local external use is also not absorbed by skin and mucous membrane.