Quinine NEW

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Introduction

Product Name :Quinine

Other name:(R)-(6-Methoxyquinolin-4-yl)((1R,2R,4R,5S)-5-vinylquinuclidin-2-yl)Methanol;(1R)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)Methanol;(-)-QUININE FOR RESOLUTION OF RACEMATES;

CAS No.: 130-95-0

MF:C20H24N2O2

MW:324.42

Appearance: White Powder

Melting Point :173-175 °C(lit.)

Boiling Point :462.75°C (rough estimate)

Density:1.1294 (rough estimate)

Storage :Keep in dark place,Sealed in dry,Room Temperature

Quinin is a substance that was first obtained by processing the bark of the cinchona tree, a South American native plant that has been used as a fever reducer by Native Americans for centuries. This substance has been used historically to treat malaria, along with some other medical conditions, and although a number of antimalarial drugs are on the market today, it is still used in some regions. It is also used commercially as an additive to tonic water, a soft drink that is used as a mixer for other drinks in addition to being consumed straight.
Nature Quinine is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine which, unlike Nature Quinine, is an anti-arrhythmic. Sulphate Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine.

Function

1.Quinine is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
 2.Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
 3.Quinine was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
 4.Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels.The mechanisms of its antimalarial effects are not well understood.

Application

An alkaloid derived from the bark of the cinchona tree.

It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.

Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.

It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. 

Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.