Silibinin NEW
| Price | Get Latest Price | ||
| Package | 1KG | 5KG | 25KG |
| Min. Order: | 1KG |
| Supply Ability: | 10 tons |
| Update Time: | 2024-03-19 |
Product Details
| Product Name: Silibinin | CAS No.: 22888-70-6 |
| Min. Order: 1KG | Purity: 99 |
| Supply Ability: 10 tons | Release date: 2024/03/19 |
| CAS: | 22888-70-6 |
| MF: | C25H22O10 |
| MW: | 482.44 |
| EINECS: | 245-302-5 |
| Product Categories: | Aromatics;Chiral Reagents;Angiogenesis InhibitorsCancer Research;Anti-proliferative AgentsNutrition Research;Angiogenesis;Biochemicals Found in Plants;Flavanones;Natural Plant Extract;Bioflavonoids;Cancer Research;Chemopreventive Agents;chemical reagent;Plant extract;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical raw material;Plant extracts;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
| Mol File: | 22888-70-6.mol |
 | |
| Silibinin Chemical Properties |
| Melting point | 164-174°C |
| alpha | D20 +11° (c = 0.25 in acetone + alcohol) |
| Boiling point | 793.0±60.0 °C(Predicted) |
| density | 1.527±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Acetone (Sparingly), DMSO, Methano (Sparingly) |
| form | Solid |
| pka | pKa 6.42±0.04 (Uncertain) |
| color | Pale Yellow |
| Water Solubility | 54mg/L(24.99 ºC) |
| Merck | 13,8607 |
| Stability: | Stable. Incompatible with strong oxidizing agents, strong bases. |
| LogP | 4.232 (est) |
| CAS DataBase Reference | 22888-70-6(CAS DataBase Reference) |
| Silibinin Usage And Synthesis |
| Chemical Properties | solid |
| Originator | Legalon,Madaus,W. Germany,1969 |
| Uses | Silibinin has been used:
|
| Uses | Labelled Silybin (S465850). Hepatoprotectant. |
| Definition | ChEBI: A flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities. |
| Manufacturing Process | Silymarin comprising polyhydroxyphenyl chromanones is recovered from the dried fruit of Silybum marianum Gaertn. by separating the fatty oils therefrom, extracting the remaining solid residue with ethyl acetate, evaporating the ethyl acetate and dissolving the dry residue in a solvent mixture comprising methanol, water and petroleum ether to form a two-phase system wherein the chromanones are contained in the lower phase, recovering the polyhydroxyphenyl chromanones from the lower phase after subjecting same to multiple counter-current contact with petroleum ether. |
| Therapeutic Function | Hepatoprotectant |
| General Description | Silibinin, a principal component of silymarin, is a flavonolignan and an orally active flavonoid. It is isolated from the seeds of milk thistle (Sylibum marianum L). |
| Biochem/physiol Actions | Silibinin functions as a hepatoprotectant in patients with acute and chronic liver injury. This flavonoid fights against various cancer cells including, prostate, skin, breast, colon, lung, bladder and hepatocellular carcinoma (HCC). Silibinin exhibits its efficacy as an anti-cancer agent by blocking the secretion of proangiogenic factors from tumor cells, and by hindering growth and inducing apoptotic death of endothelial cells. In addition, it also interrupts capillary tube formation on Matrigel. Silibinin might be a good candidate for chemoprevention of prostate cancer (PC). It might be used as a potential therapeutic regimen for the treatment of endometriosis in vitro and in vivo. |
Packing &shipping&Payment
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Shanghai Affida New Technology Center, located in Fengxian District, Shanghai. The company produces more than 1000 kinds of high-quality products I20 production lines to provide OEM services, as one of the most dynamic industry and trade integrated companies in the Chinese market.our advantage comes from our service, we can provide fast delivery. The average delivery time in peak season is less than 15 working days, and the average delivery time in off-season is less than 1 month. We have successfully transported many chemical raw materials to many countries in the world. Good feedback and repeat orders have supported the growth of our company.independent production lines, we have 20 pharmaceutical raw materials, organic solvents and other raw material production lines. In addition, we also have an API production workshop with independent research and development production lines, as well as an API research and development testing center. We can provide you with sample testing and accept small orders. Supply 99%+ quality chemical products. We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Ouda will be your strong, sincere and reliable partner in China.
Advantages:
1. Samples are provided for test;
2. Good quality products;
3. 100% secure delivery.
4. secure your money, lower the risk
5.Payment ways: Western Union, Moneygram, Bitcoin, T/T，USDT、PAYPAL
6.Delivery: EMS/ EUB/ USPS/ UPS/ TNT/ FEDEX/ DHL /DPDetc
7.Packaging:safe and discreet packaging
Our company Superiority
1 Best service, high quality and reasonable price
2. It's customers' right to choose the package (EMS, DHL, FedEx, UPS);
3. It's customers' right to choose the packing way for his products from many recent effective packing ways
4. Specials are possible when client's order is big enough, including the discount policy;
5.Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship in time;
Our company supply high quality chemical products with the most competitive prices.
If have any need or question, contact us freely.
Hope we can have chances to build good long-term cooperation.
Inquiry guide
1. Please send the quantity(Weight) to us, we will arrange our sales to provide the one-for-one service for you.
2.Then we will provide the professional quotation list for you, it will be including all the factors in whole business process(Quality, shipping, payment, files etc.).
3.If you have many products need inquiry, please send the list for us, the product clear information includes CAS + Name + quantity(Weight), we will provide the complete solution for you. We also provide the customization product.
Company Profile Introduction
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