Sodium salicylate NEW

Sodium salicylate Cas 54-21-7

Product Description

Product Name: Sodium salicylate

Synonyms:  Sodiumsalicylate

CAS No. 54-21-7

M.F.: C7H5NaO3

M.W.: 160.1

EINECS: 200-198-0

Specifications

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Sodium salicylate is the sodium salt of salicylic acid. It is an organic compound with the formula C₇H₅NaO₃.

In simpler terms, it's formed when the acidic hydrogen (H) on the -OH group of salicylic acid is replaced by a sodium ion (Na⁺).

1. Chemical Structure and Formation

• Parent Compound: Salicylic Acid (C₇H₆O₃)

• It has a benzene ring with two functional groups: a carboxylic acid group (-COOH) and an ortho-positioned phenolic hydroxyl group (-OH).

  The -COOH group is acidic.

• Formation Reaction:
  Salicylic acid reacts with a base, such as sodium hydroxide (NaOH), in a neutralization reaction. The hydrogen from the carboxylic acid group is replaced by a sodium ion.

  Chemical Equation:
  C₆H₄(OH)COOH + NaOH → C₆H₄(OH)COONa + H₂O
  (More precisely: C₆H₄(OH)COO⁻ H⁺ + Na⁺ OH⁻ → C₆H₄(OH)COO⁻ Na⁺ + H₂O)

  Molecular Structure:

2. Key Chemical Properties

• Appearance: A white, crystalline, odorless powder.

  Solubility: It is highly soluble in water and polar solvents like glycerol. This is a key difference from salicylic acid, which is poorly soluble in water. The ionic nature of the salt allows it to dissolve easily in polar water molecules.

  pH: Its aqueous solution is slightly basic to neutral (pH ~6-7) because the conjugate base of a weak acid (salicylic acid) hydrolyzes water slightly.

  Melting Point: It decomposes upon heating rather than having a clear melting point.

3. How it Works in the Body (Pharmacology)

Sodium salicylate is a key metabolite of aspirin (acetylsalicylic acid) in the human body. While aspirin itself inhibits cyclooxygenase (COX) enzymes to exert its effects, sodium salicylate has a different and more complex mechanism:

• Primary Mechanism: It is a weak anti-inflammatory and analgesic (pain-reliever). Its main action is not strong COX inhibition like aspirin. Instead, it is believed to work by suppressing the expression of the COX-2 enzyme at the genetic level (by inhibiting transcription factors like NF-κB). This means it prevents the body from producing more of the enzyme that causes inflammation and pain, rather than just blocking the existing enzyme.

  Antipyretic: It also has antipyretic (fever-reducing) effects, likely through action on the hypothalamus in the brain.

4. Common Uses

1. Medicinal:

• Analgesic and Anti-pyretic: Historically used to treat pain, fever, and inflammatory conditions like rheumatic fever and arthritis. Its use has largely been replaced by newer NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) like ibuprofen, which have a better safety profile.

  Prodrug: As the active metabolite of aspirin, it is responsible for a significant portion of aspirin's long-lasting effects.

2. Industrial and Laboratory:

• Precursor: Used in the organic synthesis of other chemicals.

  Analytical Chemistry: Sometimes used as a standard or reagent.

  Preservative: In some cosmetics and personal care products due to its mild antimicrobial properties.

Comparison with Salicylic Acid

Summary

In chemical terms, sodium salicylate is the water-soluble sodium salt of salicylic acid. It is an ionic organic compound known for its role in medicine as a pain reliever, fever reducer, and anti-inflammatory agent, primarily through a mechanism that suppresses inflammation-related gene expression.

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Different products have different MOQ, such as:

1).Peptide products, the MOQ is 1 gram level

2).Liquid products, the MOQ is usually 50-100ML

3).API,  the MOQ is 1KG

4).Intermediate products and conventional product, the MOQ is 1KG; custom-tailored products, the MOQ depends on the production process.

5).Food additives and vitamin, the MOQ is usually one package: such as Vitamin C is 25KG / drum, Vitamin E oil or Vitamin A oil  is 5KG/bag;Vitamin E powder or Vitamin A powder is 20KG / cartons.

6).Agrochemical , the MOQ is 1KG, except preparations.

6.How do we take the quality complaint ?

First of all, our quality control will reduce the quality issue to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or compensate your loss.

Company Information

Company profile

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients’ requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. 

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.

We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

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