Sulfasalazine NEW

Manufacturer Provide Veterinary Raw Materialsul CAS599-79-1 Sulfasalazine

Introduction

1.Product Name: Sulfasalazine

2.Other Name: salicylazosulfapyridine;SALAZOSULFAPYRIDINE;SULFASALAZINE

3..CAS NO:599-79-1

4.Purity: 99%min
5.Appearance:White Powder

6.Molecular formula: C18H14N4O5S

7.Molecular weight:398.39

8.Melting Point :260-265 °C (dec.)(lit.)

9.Boiling Point :689.3±65.0 °C

10.Density :1.3742 g/mL at 20 °C

11.Storage:Keep in dark place,Inert atmosphere,Room temperature

Sulfasalazine is an antiinflammatory agent that inhibits GSH-H-transferase. Sulfasalazine largely inhibits NF-κB activation and induces apoptosis in T-lymphocytes. The compound also engages neutrophil apoptosis that can be abrogated by Tyr-K inhibitors, PKA inhibitors, or antioxidants. Sulfasalazine is shown to inhibit basic fibroblast growth factor-induced endothelial cell chemotaxis. Sulfasalazine is an inhibitor of TNFα and an activator of PPARγ.