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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Neuronal Signaling>5-HT Receptor agonists>Tianeptine sodium salt
Tianeptine sodium salt
  • Tianeptine sodium salt

Tianeptine sodium salt NEW

Price $1800 $1700 $1600
Package ≥1kg ≥10kg ≥100kg
Min. Order: 1kg
Supply Ability: 200KG/Month
Update Time: 2024-03-24

Product Details

Product Name: Tianeptine sodium salt CAS No.: 30123-17-2
EC-No.: 250-059-3 Min. Order: 1kg
Purity: 99% Supply Ability: 200KG/Month
Release date: 2024/03/24

Tianeptine sodium salt

CAS: 30123-17-2

Molecular Formula: C21H24ClN2NaO4S

Namesodium 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate S,S-dioxide
SynonymsS-1574
Stablon
TIANEPTINE SODIUM
TIANEPTINE SODIUM SALT
Tianeptine sodium salt
Sodium 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate
sodium 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate S,S-dioxide
3-Chloro-6,11-dihydro-6-methyl-11-[6-(sodiooxycarbonyl)hexylamino]dibenzo[c,f][1,2]thiazepine 5,5-dioxide
7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic Acid S,S-Dioxide Sodium Salt
7-[(3-chloro-6,11-dihydro-6-methyl-dibenzo[c,f][1,2]thiazepine-11-yl)amino]heptanoic acid s,s dioxide sodium salt
[7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepine 5,5-dioxide)-11-ylamino]heptanoic acid]sodium salt
CAS30123-17-2
EINECS250-059-3
InChIInChI=1/C21H25ClN2O4S.Na/c1-24-18-9-6-5-8-16(18)21(23-13-7-3-2-4-10-20(25)26)17-12-11-15(22)14-19(17)29(24,27)28;/h5-6,8-9,11-12,14,21,23H,2-4,7,10,13H2,1H3,(H,25,26);/q;+1
InChIKeyZLBSUOGMZDXYKE-UHFFFAOYSA-M

30123-17-2 - Physico-chemical Properties

Molecular FormulaC21H24ClN2NaO4S
Molar Mass458.93
Melting Point1800C
SolubilityDMSO: ≥20mg/mL
Appearancesolid
Colorwhite to tan
Merck14,9420
Storage ConditionDesiccate at RT
StabilityStable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.
In vivo studyIn unstressed rats, Tianeptine treatment prevents CMS-induced increases in corticotropin-releasing factor (CRF)mRNA levels in dBNST, and reduce the mRNA level of corticotropin releasing factor (CRF) in dBNST. Tianeptine treatment significantly reduced CRF mRNA levels in ventral BNST and CEA in stress-avoidance controls as well as in CMS-exposed rats. In the basolateral nucleus (BLA) of the amygdala of anesthetized rats, Tianeptine blocked the stress-induced enhancement of PB in the CA1 region without affecting the stress-induced enhancement of LTP. In the amygdala, hippocampus and LTP of anesthetized rats, Tianeptine administered enhanced PB enhancement under non-stress conditions. In rats, Tianeptine attenuates the behavioral signs of peripheral-induced, but not central, LPS, or IL-1β-induced, morbid behavior. In rats, Tianeptine causes the normalized ratio of the amplitude ratio of the NMDA receptor to AMPA/kainate receptor-mediated currents and prevents the attenuation of stress-induced NMDA-EPSCS inactivation. Both in control and stressed animals, in the rat temporal cortex and hippocampal dentate gyrus, Tianeptine significantly reduced apoptosis, but had no effect on the Horn of Africa Ammons. Only in the nucleus accumbens, Tianeptine(2.5 mg/kg, I. P.) increased extracellular dopamine. In both nucleus accumbens and striatum, Tianeptine significantly increased the extracellular concentrations of hydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA).

Company introduction:

Shijiazhuang Jianxin Biotechnology Co., Ltd. was established in December 2023 with a registered capital of five hundred thousand yuan, located in Xingtang Chemical Industry Park, Shijiazhuang City, Hebei Province. It is an important part of Xingtang Development Zone and a key chemical new material enterprise. Adhering to the concept of integrity, green, innovation and win-win development, with a strong R & D team and scientific management mode, the company is committed to the technology development, technology transformation and production and operation of new energy materials. The company has 48 employees, including 12 R&D personnel. Since 2023, it has successfully researched and developed electrolyte additives such as 1, 3, 6-hexane trinitrile (HTCN), and pharmaceutical intermediates such as 2-phenylacetamide and tryptamine.

Article illustration

RAQ:

1.who are we?
Shijiazhuang Jianxin Biotechnology Co., LTD

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
2-phenylacetamide
Tryptamine PMK ethyl glycidate etc.

4. why should you buy from us not from other suppliers?
Product quality is good, the staff through professional training, good after-sales, fast logistics, transportation safety.

5. what services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW,FCA,DDP,Express Delivery

Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,D/P D/A,MoneyGram,Credit Card,PayPal,Western Union,Cash,Escrow;

 

6.Contact information

Email: liyingjian1997@gmail.com

Tel/Wechat: +8617692708569

Whatsapp: +8617349893169


Company Profile Introduction

Shijiazhuang Jianxin Biotechnology Co., Ltd. was established in December 2023 with a registered capital of five hundred thousand yuan, located in Xingtang Chemical Industry Park, Shijiazhuang City, Hebei Province. It is an important part of Xingtang Development Zone and a key chemical new material enterprise. Adhering to the concept of integrity, green, innovation and win-win development, with a strong R & D team and scientific management mode, the company is committed to the technology development, technology transformation and production and operation of new energy materials. The company has 48 employees, including 12 R&D personnel. Since 2023, it has successfully researched and developed electrolyte additives such as 1, 3, 6-hexane trinitrile (HTCN), and pharmaceutical intermediates such as 2-phenylacetamide and tryptamine.

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Shijiazhuang Jianxin Biotechnology Co., LTD

1YR ChinaChina
  • Since: 2023-11-27
  • Address: No.17, Xinglong West Street, North Longgang Village, Nanqiao Town, Xingtang County, Shijiazhuang Cit
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