Product Details
| Product Name:
Zoniporide |
CAS No.:
241800-98-6 |
| Purity:
99.74% |
Supply Ability:
10g |
| Release date:
2026/04/22 |
Product Introduction
Bioactivity
| Name | Zoniporide |
| Description | Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits the uptake of 22Na+ by fibroblasts expressing human NHE-1 in a concentration-dependent manner, inhibits platelet swelling, and can be used in the study of cardiovascular diseases. |
| In vivo | In rats, Zoniporide (1 mg/kg; i.v.) shows the AUC0-∞ = 0.07 μg h/mL, and t1/2 are 0.5 hours, respectively. [1]
In open chest anesthetized rabbits, Zoniporide (0.25, 1, 4 mg/kg; i.v.) dose-dependently reduces infarct size with an ED50 = 0.45 mg/kg/h. Zoniporide exhibits moderate plasma protein binding with t1/2 of 1.5h in monkeys. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 100 mg/mL (312.16 mM), Sonication is recommended.
|
| Keywords | Zoniporide | SodiumChannel | Sodium Channel | NHE1 |
| Inhibitors Related | Phenytoin sodium | Procaine | Ranolazine dihydrochloride | Tetracaine hydrochloride | Lidocaine | Safinamide | Permethrin | Valproic Acid | L-Aspartic aicd sodium | Lidocaine hydrochloride | Mebeverine hydrochloride | Dibucaine |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Sodium Channel Targeted Library | Neuroprotective Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$2500.00/100mg |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-04-22 |
United States